Ferroptosis in tumor immunity and therapy

C Gong, Q Ji, M Wu, Z Tu, K Lei, M Luo… - Journal of Cellular …, 2022 - Wiley Online Library
Ferroptosis is a type of regulated cell death (RCD), and it plays an important role in the
occurrence of diseases, especially the development of tumors. Ferroptosis of tumor cells …

Role of ferroptosis in gastrointestinal tumors: From mechanisms to therapies

C Si, X Zhou, J Deng, S Ye, L Kong… - Cell Biology …, 2022 - Wiley Online Library
Ferroptosis is an iron‐dependent nonapoptotic regulated cell death, which is mainly caused
by an abnormal increase in lipid oxygen free radicals and an imbalance in redox …

Effect of tumor microenvironment on ferroptosis: inhibition or promotion

Z Xia, Y Quan - Frontiers in Oncology, 2023 - frontiersin.org
Ferroptosis is a type of lipid peroxidation-induced, iron-dependent programmed cell death.
Emerging evidence suggests that ferroptosis is intimately connected to tumorigenesis …

Deciphering the potential roles of ferroptosis in regulating tumor immunity and tumor immunotherapy

X Gu, Y Liu, X Dai, YG Yang, X Zhang - Frontiers in Immunology, 2023 - frontiersin.org
Cancer immunotherapies, including immune checkpoint inhibition (ICI) and adoptive
immune cells therapy, are promising therapeutic strategies. They reactivate the function of …

[HTML][HTML] Targeting ferroptosis for cancer therapy: iron metabolism and anticancer immunity

L Luo, H Wang, W Tian, J Zeng, Y Huang… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Ferroptosis is a new form of programmed cell death characterized by iron-dependent
accumulation of lipid peroxidation, which plays an important role in cancer biology …

[HTML][HTML] Current Progress of Ferroptosis Study in Hepatocellular Carcinoma

X Zhu, X Sha, Y Zang, Q Ren, S Zhang… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Ferroptosis, an emerging type of programmed cell death, is initiated by iron-dependent and
excessive ROS-mediated lipid peroxidation, which eventually leads to plasma membrane …

Ferroptosis and cancer immunotherapy

J Yin, X Meng, L Peng, W Xie, X Liu… - Current Molecular …, 2023 - ingentaconnect.com
Traditional treatment strategies for cancer are unsatisfactory. As a nonapoptotic cell death
process and owning to the characteristics of iron-dependent lipid peroxide accumulation …

Ferroptosis is an effective strategy for cancer therapy

A Khan, Y Huo, Y Guo, J Shi, Y Hou - Medical Oncology, 2024 - Springer
Ferroptosis is a form of intracellular iron-dependent cell death that differs from necrosis,
autophagy and apoptosis. Intracellular iron mediates Fenton reaction resulting in lipid …

Ferroptosis: a double-edged sword mediating immune tolerance of cancer

Q Dang, Z Sun, Y Wang, L Wang, Z Liu, X Han - Cell death & disease, 2022 - nature.com
The term ferroptosis was put forward in 2012 and has been researched exponentially over
the past few years. Ferroptosis is an unconventional pattern of iron-dependent programmed …

Targeting ferroptosis in colorectal cancer

X Liang, Z You, X Chen, J Li - Metabolites, 2022 - mdpi.com
Ferroptosis is a unique way of regulating cell death (RCD), which is quite different from other
programmed cell deaths such as autophagy. It presents iron overload, accumulation of …