Ferroptosis is a type of cell death that depends on iron and reactive oxygen species (ROS).
The accumulation of iron and lipid peroxidation primarily initiates oxidative membrane …

Colorectal cancer (CRC) is a common malignant tumor associated with high morbidity and
mortality. Despite an increase in early screening and treatment options, people with CRC …

Ferroptosis is an iron-dependent regulated form of cell death caused by excessive lipid
peroxidation. This form of cell death differed from known forms of cell death in morphological …

Purpose Hepatocellular carcinoma (HCC) is a complicated disease with low survival rate
due to frequent recurrence and the lack of efficient therapies. For advanced HCC, sorafenib …

Colorectal cancer (CRC) is the third leading cause of cancer deaths worldwide and is
characterised by frequently mutated genes, such as APC, TP53, KRAS and BRAF. The …

For a long time, the morbidity and mortality rates of hepatocellular carcinoma (HCC) have
remained high. Since the concept of ferroptosis was introduced in 2012, researchers' …

Iron is an essential element for almost all living things. Both iron excess and iron deficiency
can damage the body's health, but the body has developed complex mechanisms to …

Ferroptosis is an iron-dependent mode of programmed cell death characterized by Reactive
Oxygen Species (ROS) accumulation lipid peroxidation and glutathione depletion. It is a …

Ferroptosis is an iron-dependent form of regulated cell death that is triggered by the toxic
build-up of lipid peroxides on cellular membranes. In recent years, ferroptosis has garnered …

Triggering ferroptosis, an iron-dependent form of cell death, has recently emerged as an
approach for treating cancer. A better understanding of the role and regulation of ferroptosis …