Importance Cell-based assays (CBAs) were shown to improve detection of acetylcholine
receptor (AChR) antibodies in patients with myasthenia gravis (MG). Herein, we asked …

Objective To compare specificity and sensitivity of a commercially available fixed cell-based
assay (F-CBA) to radioimmunoprecipitation assay (RIPA) for acetylcholine receptor antibody …

Background and Objectives Live cell-based assay (CBA) can detect acetylcholine receptors
(AChRs) or muscle-specific tyrosine kinase (MuSK) antibodies (Abs) in a proportion of …

Objective Patients with myasthenia gravis without acetylcholine receptor (AChR) or muscle-
specific kinase (MuSK) antibodies detected by radioimmunoprecipitation assays (RIAs) are …

Acetylcholine receptor (AChR) binding and AChR modulating antibodies were found with
approximately the same frequency (86%) in 349 patients with myasthenia gravis (MG) …

Antibodies to acetylcholine receptor (AChR) are found in 85% of patients with myasthenia
gravis (seropositive MG [SPMG]) and are thought to be pathogenic; but in 15% of MG …

Background Clustered acetylcholine receptor antibodies (clustered AChR-Abs) have been
detected in a proportion of patients with previously “seronegative”(SN) generalized …

Only around 80% of patients with generalized myasthenia gravis (MG) have serum
antibodies to acetylcholine receptor [AChR; acetylcholine receptor antibody positive …

PURPOSE: To establish non-radioactive assays for detection of antibodies (Abs) to the
acetylcholine receptor (AChR) and to muscle specific kinase (MuSK). To show that the …

Importance The sensitivity of acetylcholine receptor (AChR) antibody testing is thought to be
lower in ocular myasthenia gravis (OMG) compared with generalized disease, although …