Clinical features and diagnostic usefulness of antibodies to clustered acetylcholine receptors in the diagnosis of seronegative myasthenia gravis
PMR Cruz, M Al-Hajjar, S Huda, L Jacobson… - JAMA …, 2015 - jamanetwork.com
Importance Cell-based assays (CBAs) were shown to improve detection of acetylcholine
receptor (AChR) antibodies in patients with myasthenia gravis (MG). Herein, we asked …
receptor (AChR) antibodies in patients with myasthenia gravis (MG). Herein, we asked …
[HTML][HTML] Comparison of fixed cell-based assay to radioimmunoprecipitation assay for acetylcholine receptor antibody detection in myasthenia gravis
Objective To compare specificity and sensitivity of a commercially available fixed cell-based
assay (F-CBA) to radioimmunoprecipitation assay (RIPA) for acetylcholine receptor antibody …
assay (F-CBA) to radioimmunoprecipitation assay (RIPA) for acetylcholine receptor antibody …
Comparison of fixed and live cell-based assay for the detection of AChR and MuSK antibodies in myasthenia gravis
G Spagni, M Gastaldi, P Businaro… - Neurology …, 2022 - AAN Enterprises
Background and Objectives Live cell-based assay (CBA) can detect acetylcholine receptors
(AChRs) or muscle-specific tyrosine kinase (MuSK) antibodies (Abs) in a proportion of …
(AChRs) or muscle-specific tyrosine kinase (MuSK) antibodies (Abs) in a proportion of …
Clinical value of cell-based assays in the characterisation of seronegative myasthenia gravis
Objective Patients with myasthenia gravis without acetylcholine receptor (AChR) or muscle-
specific kinase (MuSK) antibodies detected by radioimmunoprecipitation assays (RIAs) are …
specific kinase (MuSK) antibodies detected by radioimmunoprecipitation assays (RIAs) are …
Clinical correlations of antibodies that bind, block, or modulate human acetylcholine receptors in myasthenia gravis.
FM Howard Jr, VA Lennon, JON Finley… - Annals of the New …, 1987 - europepmc.org
Acetylcholine receptor (AChR) binding and AChR modulating antibodies were found with
approximately the same frequency (86%) in 349 patients with myasthenia gravis (MG) …
approximately the same frequency (86%) in 349 patients with myasthenia gravis (MG) …
IgG from “seronegative” myasthenia gravis patients binds to a muscle cell line, TE671, but not to human acetylcholine receptor
F Blaes, D Beeson, P Plested, B Lang… - Annals of Neurology …, 2000 - Wiley Online Library
Antibodies to acetylcholine receptor (AChR) are found in 85% of patients with myasthenia
gravis (seropositive MG [SPMG]) and are thought to be pathogenic; but in 15% of MG …
gravis (seropositive MG [SPMG]) and are thought to be pathogenic; but in 15% of MG …
Presence and pathogenic relevance of antibodies to clustered acetylcholine receptor in ocular and generalized myasthenia gravis
Background Clustered acetylcholine receptor antibodies (clustered AChR-Abs) have been
detected in a proportion of patients with previously “seronegative”(SN) generalized …
detected in a proportion of patients with previously “seronegative”(SN) generalized …
IgG1 antibodies to acetylcholine receptors in 'seronegative'myasthenia gravis
Only around 80% of patients with generalized myasthenia gravis (MG) have serum
antibodies to acetylcholine receptor [AChR; acetylcholine receptor antibody positive …
antibodies to acetylcholine receptor [AChR; acetylcholine receptor antibody positive …
Non-radioactive serological diagnosis of myasthenia gravis and clinical features of patients from Tianjin, China
PURPOSE: To establish non-radioactive assays for detection of antibodies (Abs) to the
acetylcholine receptor (AChR) and to muscle specific kinase (MuSK). To show that the …
acetylcholine receptor (AChR) and to muscle specific kinase (MuSK). To show that the …
Clinical utility of acetylcholine receptor antibody testing in ocular myasthenia gravis
CE Peeler, LB De Lott, L Nagia, J Lemos… - JAMA …, 2015 - jamanetwork.com
Importance The sensitivity of acetylcholine receptor (AChR) antibody testing is thought to be
lower in ocular myasthenia gravis (OMG) compared with generalized disease, although …
lower in ocular myasthenia gravis (OMG) compared with generalized disease, although …
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