Non–Small-Cell Lung Cancer: Treatment of Late Stage Disease: Chemotherapeutics and New Frontiers

RJ Scheff, BJ Schneider - Seminars in interventional radiology, 2013 - thieme-connect.com
Systemic therapy should be considered in patients with advanced non–small cell lung
cancer (NSCLC) who are no longer amenable to local therapies. Systemic therapy has been …

Molecular targets in non–small cell lung cancer

R Griffin, RA Ramirez - Ochsner Journal, 2017 - ochsnerjournal.org
Background: Lung cancer is the second most common cancer in the United States among
men and women, and it is the most common cause of cancer-related death. Non–small cell …

Therapeutic advances in non‐small cell lung cancer: Focus on clinical development of targeted therapy and immunotherapy

Y Cheng, T Zhang, Q Xu - MedComm, 2021 - Wiley Online Library
Lung cancer still contributes to nearly one‐quarter cancer‐related deaths in the past
decades, despite the rapid development of targeted therapy and immunotherapy in non …

Targeted therapy of oncogenic-driven advanced non-small cell lung cancer: recent advances and new perspectives

C Genova, G Rossi, M Tagliamento… - Expert review of …, 2020 - Taylor & Francis
Introduction: The discovery of new actionable oncogenic drivers has led to the development
of effective antineoplastic targeted agents in advanced non-small cell lung cancer (NSCLC) …

[HTML][HTML] Emerging targeted therapies in advanced non-small-cell lung cancer

S Li, GS de Camargo Correia, J Wang, R Manochakian… - Cancers, 2023 - mdpi.com
Simple Summary The discovery of actionable oncogenic driver mutations in non-small-cell
lung cancer (NSCLC) has revolutionized the treatment and prognosis of this dreadful …

[HTML][HTML] Promising targets and current clinical trials in metastatic non-squamous NSCLC

A Zer, N Leighl - Frontiers in Oncology, 2014 - frontiersin.org
Lung adenocarcinoma is the most common subtype of lung cancer today. With the discovery
of epidermal growth factor receptor (EGFR) mutations, anaplastic lymphoma kinase (ALK) …

[HTML][HTML] Chemotherapy for advanced non-small cell lung cancer with a focus on squamous cell carcinoma

K Kuribayashi, N Funaguchi… - Journal of cancer research …, 2016 - journals.lww.com
Lung cancers are broadly divided into small-cell lung cancer (SCLC) and non-SCLC
(NSCLC), and the treatments for each differ. NSCLC includes squamous cell carcinoma …

[HTML][HTML] Non-small-cell lung cancer: New rare targets—New targeted therapies—state of the art and future directions

K Stencel, I Chmielewska, J Milanowski, R Ramlau - Cancers, 2021 - mdpi.com
Simple Summary The use of novel therapeutic drugs in lung cancer has changed the
paradigm of the diagnosis and treatment of lung cancer. Due to the development of …

emerging therapeutic targets in non–small cell lung cancer

GK Dy, AA Adjei - Proceedings of the American Thoracic Society, 2009 - atsjournals.org
Over the last decade, systemic cancer therapies have evolved to exploit the growing
knowledge of molecular aberrations involved in the development and progression of lung …

[PDF][PDF] NSCLC: an update of driver mutations, their role in pathogenesis and clinical significance

RC Black, H Khurshid - Rhode Island medical journal, 2015 - rimed.org
Lung cancer is the most common malignancy in the US and causes the most cancer-related
deaths. Non-smallcell lung carcinoma (NSCLC) accounts for the majority of cases. NSCLC …