Molecular targeted therapy in the treatment of advanced stage non‐small cell lung cancer (NSCLC)
N Barr Kumarakulasinghe, N Zanwijk, RA Soo - Respirology, 2015 - Wiley Online Library
Historically, patients with advanced stage non‐small cell lung cancer (NSCLC) were treated
with chemotherapy alone, but a therapeutic plateau has been reached. Advances in the …
with chemotherapy alone, but a therapeutic plateau has been reached. Advances in the …
Second-line treatment of non-small cell lung cancer: new developments for tumours not harbouring targetable oncogenic driver mutations
PC Barnfield, PM Ellis - Drugs, 2016 - Springer
Platinum-based doublet chemotherapy with or without bevacizumab is the standard of care
for the initial management of advanced and metastatic non-small cell lung cancer (NSCLC) …
for the initial management of advanced and metastatic non-small cell lung cancer (NSCLC) …
[HTML][HTML] Novel therapeutic targets in non-small cell lung cancer
F Janku, I Garrido-Laguna, LB Petruzelka… - Journal of Thoracic …, 2011 - Elsevier
The development of personalized medicine with a focus on novel targeted therapies has
supplanted the one-size-fits-all approach to the treatment of many cancers, including non …
supplanted the one-size-fits-all approach to the treatment of many cancers, including non …
Individualized therapy in non-small-cell lung cancer: future versus current clinical practice
R Perez-Soler - Oncogene, 2009 - nature.com
Despite advances in the management of non-small-cell lung cancer (NSCLC), including the
introduction of targeted therapies such as epidermal growth factor receptor tyrosine kinase …
introduction of targeted therapies such as epidermal growth factor receptor tyrosine kinase …
Precision management of advanced non–small cell lung cancer
CY Yang, JCH Yang, PC Yang - Annual review of medicine, 2020 - annualreviews.org
The rapid evolution of treatment for advanced lung cancer is a story of how scientists have
struggled to move from nonselective cytotoxic chemotherapy to personalized precision …
struggled to move from nonselective cytotoxic chemotherapy to personalized precision …
[HTML][HTML] Should progression-free survival be the primary measure of efficacy for advanced NSCLC therapy?
Non-small-cell lung cancer (NSCLC) is a leading cause of malignancy-related mortality in
the Western world. Despite advances in early detection and standard treatment, NSCLC is …
the Western world. Despite advances in early detection and standard treatment, NSCLC is …
[HTML][HTML] Historical evolution of second-line therapy in non-small cell lung cancer
C Lazzari, A Bulotta, M Ducceschi, MG Vigano… - Frontiers in …, 2017 - frontiersin.org
Innovative therapeutic agents have significantly improved outcome with an acceptable
safety profile in a substantial proportion of non-small cell lung cancer (NSCLC) patients, who …
safety profile in a substantial proportion of non-small cell lung cancer (NSCLC) patients, who …
Novel targeted therapies for advanced non-small lung cancer
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer accounting for
almost 80%–85% of all lung cancer cases. Unfortunately, more than half of the patients will …
almost 80%–85% of all lung cancer cases. Unfortunately, more than half of the patients will …
[HTML][HTML] Breakthrough in targeted therapy for non-small cell lung cancer
Z Ye, Y Huang, J Ke, X Zhu, S Leng, H Luo - Biomedicine & …, 2021 - Elsevier
Non-small cell lung cancer (NSCLC) remains by far the single most common malignancy of
lung cancer which causes more and more mortality in recent years. NSCLC accounts for …
lung cancer which causes more and more mortality in recent years. NSCLC accounts for …
Targeted therapies in combination with chemotherapy in non–small cell lung cancer
DH Johnson - Clinical cancer research, 2006 - AACR
With rare exceptions, attempts to combine so-called targeted agents with standard cytotoxic
chemotherapy in advanced non–small cell lung cancer have yielded disappointing results …
chemotherapy in advanced non–small cell lung cancer have yielded disappointing results …