Reactive oxygen species in cancer cells: live by the sword, die by the sword

PT Schumacker - Cancer cell, 2006 - cell.com
Reactive oxygen species and tumor biology are intertwined in a complex web, making it
difficult to understand which came first, whether oxidants are required for tumor cell growth …

Reactive oxygen species in cancer: a dance with the devil

PT Schumacker - Cancer cell, 2015 - cell.com
Reactive oxygen species (ROS) can initiate cancer, but oxidant generation in tumors leaves
them vulnerable to further stresses. In this issue of Cancer Cell, Harris and colleagues show …

Reactive oxygen species in cancer

GY Liou, P Storz - Free radical research, 2010 - Taylor & Francis
Elevated rates of reactive oxygen species (ROS) have been detected in almost all cancers,
where they promote many aspects of tumour development and progression. However …

ROS signalling in the biology of cancer

JN Moloney, TG Cotter - Seminars in cell & developmental biology, 2018 - Elsevier
Increased reactive oxygen species (ROS) production has been detected in various cancers
and has been shown to have several roles, for example, they can activate pro-tumourigenic …

ROS in cancer: the burning question

IIC Chio, DA Tuveson - Trends in molecular medicine, 2017 - cell.com
An unanswered question in human health is whether antioxidation prevents or promotes
cancer. Antioxidation has historically been viewed as chemopreventive, but emerging …

Oxidative stress in cancer cell metabolism

S Arfin, NK Jha, SK Jha, KK Kesari, J Ruokolainen… - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are important in regulating normal cellular processes
whereas deregulated ROS leads to the development of a diseased state in humans …

The two faces of reactive oxygen species in cancer

CR Reczek, NS Chandel - Annual review of cancer biology, 2017 - annualreviews.org
Reactive oxygen species (ROS), now appreciated for their cellular signaling capabilities,
have a dual role in cancer. On the one hand, ROS can promote protumorigenic signaling …

Reactive oxygen species and cancer paradox: to promote or to suppress?

S Galadari, A Rahman, S Pallichankandy… - Free Radical Biology …, 2017 - Elsevier
Reactive oxygen species (ROS), a group of highly reactive ions and molecules, are
increasingly being appreciated as powerful signaling molecules involved in the regulation of …

The role of reactive oxygen species and metabolism on cancer cells and their microenvironment

A Costa, A Scholer-Dahirel… - Seminars in cancer biology, 2014 - Elsevier
Compelling evidence show that reactive oxygen species (ROS) levels are finely regulated in
the cell and can act as “second messengers” in response to diverse stimuli. In tumor …

[HTML][HTML] Reactive oxygen species: role in the development of cancer and various chronic conditions

G Waris, H Ahsan - Journal of carcinogenesis, 2006 - ncbi.nlm.nih.gov
Oxygen derived species such as superoxide radical, hydrogen peroxide, singlet oxygen and
hydroxyl radical are well known to be cytotoxic and have been implicated in the etiology of a …