One of the most important functions of the skin besides regulating internal body temperature
includes formation of the barrier between the organism and the external environment, hence …

Autoimmune blistering diseases comprise a group of heterogenous conditions characterized
by the loss of tolerance and subsequent development of autoantibodies targeting epidermal …

Autoimmune diseases are characterized by defined self‐antigens, organ specificity,
autoreactive T cells and/or autoantibodies that can transfer disease. Autoimmune blistering …

Autoimmune bullous skin diseases are characterized by autoantibodies and T cells specific
to structural proteins maintaining cell–cell and cell–matrix adhesion in the skin. Existing …

Cutaneous autoimmune blistering diseases are associated with tissue injury and fluid
accumulation within the skin. The initial trigger for the organ-specific damage is …

Autoimmune skin diseases represent a heterogeneous group of disorders with grossly
diverging clinical manifestations but partly shared underlying immunological mechanisms …

Blister formation in skin and mucous membranes results from a loss of cell-cell or cell-matrix
adhesion and is a common outcome of pathological events in a variety of conditions …

Autoimmune bullous diseases are a heterogeneous group of disorders that can be
subdivided according to the level of split formation in the intraepidermal blistering …

Detlef Zillikens, MD, director and chair of the Department of Dermatology at the University of
Lübeck, Lübeck, Germany, died in September 2022, aged only 64. He dedicated his …

Fundamental advances in the fields of molecular biology and immunology have facilitated
investigation of the autoimmune blistering disorders. Recently, the use of human …