The formalin test has been proposed as an animal model of pain produced by tissue injury.
Although biphasic nociceptive responses to formalin injection have been well documented …

This study evaluated the role of nitric oxide (NO) in spinal cord nociceptive transmission
during peripheral inflammation evoked by formalin injection into the rat paw, using N …

A comparison was made of spontaneous nociceptive behaviors elicited by subcutaneous
injection of formalin (0.5–10.0%) into the plantar or dorsal surface of the right hindpaw in …

Formalin injected subcutaneously into the hindpaw of the rat produces an animal model of
inflammation that exhibits a phasic component and a tonic component of pain. We evaluated …

Nociceptive c‐fos expressions in the dorsal horn following intraplantar injection of two kinds
of algogenic agents combined with different doses of nitric oxide (NO) synthase inhibitor (Nω …

To assess the possible role of spinal nitric oxide (NO) synthesis in nociceptive processing,
we examined the effect of intrathecal (it) injection of arginine analogs that act as alternate …

Objective To investigate the effects of nitric oxide (NO) with different doses on modulation of
inflammatory pain, and its possible mechanisms. Methods NO precursor L-arginine (L-Arg) …

1 We investigated the effects of intraplantar (i. pl.) administration of l‐arginine and NG‐nitro‐l‐
arginine methyl ester (l‐NAME) on formalin‐induced behavioural nociception in the mouse …

The aim of the present study was to investigate the contribution of spinal nitric oxide (NO) to
the antinociceptive effects of emulsified isofluane in rats. 2. The formalin test was used to …

Previous work has demonstrated that pain facilitation can occur following injection of
subcutaneous irritants, such as formalin. Such studies have focused on apparent pain …