Diet-induced obesity reduces the responsiveness of the peripheral taste receptor cells

AB Maliphol, DJ Garth, KF Medler - PloS one, 2013 - journals.plos.org
Introduction Obesity is a growing epidemic that causes many serious health related
complications. While the causes of obesity are complex, there is conclusive evidence that …

Differential effects of diet and weight on taste responses in diet‐induced obese mice

ZC Ahart, LE Martin, BR Kemp, D Dutta Banik… - …, 2020 - Wiley Online Library
Objective Previous studies have reported that individuals with obesity have reduced taste
perception, but the relationship between obesity and taste is poorly understood. Earlier work …

Taste responses in the nucleus of the solitary tract of awake obese rats are blunted compared with those in lean rats

MS Weiss, A Hajnal, K Czaja… - Frontiers in Integrative …, 2019 - frontiersin.org
Taste perception changes with obesity but the underlying neural changes remain poorly
understood. To address this issue, we recorded taste responses from single cells in the …

Obesity-induced taste dysfunction, and its implications for dietary intake

F Harnischfeger, R Dando - International Journal of Obesity, 2021 - nature.com
The incidence of obesity has dramatically increased in recent years, and poses a public
health challenge for which an effective and scalable intervention strategy is yet to be found …

Impact of obesity on taste receptor expression in extra-oral tissues: emphasis on hypothalamus and brainstem

D Herrera Moro Chao, C Argmann, M Van Eijk… - Scientific reports, 2016 - nature.com
Sweet perception promotes food intake, whereas that of bitterness is inhibitory. Surprisingly,
the expression of sweet G protein-coupled taste receptor (GPCTR) subunits (T1R2 and …

Altered pontine taste processing in a rat model of obesity

P Kovacs, A Hajnal - Journal of neurophysiology, 2008 - journals.physiology.org
The increased palatability of modern diet contributes to eating beyond homeostatic need
and in turn to the growing prevalence of obesity. How palatability is coded in taste-evoked …

Brain imaging of taste perception in obesity: a review

C Kure Liu, PV Joseph, DE Feldman, DS Kroll… - Current nutrition …, 2019 - Springer
Abstract Purpose of Review We summarize neuroimaging findings related to processing of
taste (fat, salt, umami, bitter, and sour) in the brain and how they influence hedonic …

Taste transductions in taste receptor cells: basic tastes and moreover

S Iwata, R Yoshida, Y Ninomiya - Current pharmaceutical …, 2014 - ingentaconnect.com
In the oral cavity, taste receptor cells dedicate to detecting chemical compounds in foodstuffs
and transmitting their signals to gustatory nerve fibers. Heretofore, five taste qualities (sweet …

Modulation of taste responsiveness and food preference by obesity and weight loss

HR Berthoud, H Zheng - Physiology & behavior, 2012 - Elsevier
Palatable foods lead to overeating, and it is almost a forgone conclusion that it is also an
important contributor to the current obesity epidemic–there is even talk about food addiction …

Shorter-lived neural taste representations in obese compared to lean individuals

S Hardikar, R Wallroth, A Villringer, K Ohla - Scientific reports, 2018 - nature.com
Previous attempts to uncover a relation between taste processing and weight status have
yielded inconclusive results leaving it unclear whether lean and obese individuals process …