[HTML][HTML] Systemic and ocular fluid compounds as potential biomarkers in age-related macular degeneration
E Kersten, CC Paun, RL Schellevis, CB Hoyng… - survey of …, 2018 - Elsevier
Biomarkers can help unravel mechanisms of disease and identify new targets for therapy.
They can also be useful in clinical practice for monitoring disease progression, evaluation of …
They can also be useful in clinical practice for monitoring disease progression, evaluation of …
Risk factors and biomarkers of age-related macular degeneration
NG Lambert, H ElShelmani, MK Singh… - Progress in retinal and …, 2016 - Elsevier
A biomarker can be a substance or structure measured in body parts, fluids or products that
can affect or predict disease incidence. As age-related macular degeneration (AMD) is the …
can affect or predict disease incidence. As age-related macular degeneration (AMD) is the …
Metabolomic profiling of the aqueous humor in patients with wet age-related macular degeneration using UHPLC–MS/MS
G Han, P Wei, M He, H Teng, Y Chu - Journal of proteome …, 2020 - ACS Publications
Assessing metabolomic alterations in age-related macular degeneration (AMD) can provide
insights into its pathogenesis. We compared the metabolomic profiles of the aqueous humor …
insights into its pathogenesis. We compared the metabolomic profiles of the aqueous humor …
Metabolomics in age-related macular degeneration: a systematic review
XW Hou, Y Wang, CW Pan - Investigative ophthalmology & …, 2020 - iovs.arvojournals.org
Purpose: Age-related macular degeneration (AMD) is one of the leading causes of
blindness among the elderly, and the exact pathogenesis of the AMD remains unclear. The …
blindness among the elderly, and the exact pathogenesis of the AMD remains unclear. The …
Human plasma metabolomics study across all stages of age-related macular degeneration identifies potential lipid biomarkers
Purpose To characterize the plasma metabolomic profile of patients with age-related
macular degeneration (AMD) using mass spectrometry (MS). Design Cross-sectional …
macular degeneration (AMD) using mass spectrometry (MS). Design Cross-sectional …
Human plasma metabolomics in age-related macular degeneration: meta-analysis of two cohorts
The pathogenesis of age-related macular degeneration (AMD), a leading cause of blindness
worldwide, remains only partially understood. This has led to the current lack of accessible …
worldwide, remains only partially understood. This has led to the current lack of accessible …
[HTML][HTML] Integrating metabolomics, genomics, and disease pathways in age-related macular degeneration: the EYE-RISK consortium
IE Acar, L Lores-Motta, JM Colijn, MA Meester-Smoor… - Ophthalmology, 2020 - Elsevier
Purpose The current study aimed to identify metabolites associated with age-related
macular degeneration (AMD) by performing the largest metabolome association analysis in …
macular degeneration (AMD) by performing the largest metabolome association analysis in …
Metabolomics and age-related macular degeneration
Age-related macular degeneration (AMD) leads to irreversible visual loss, therefore, early
intervention is desirable, but due to its multifactorial nature, diagnosis of early disease might …
intervention is desirable, but due to its multifactorial nature, diagnosis of early disease might …
Plasma metabolomic study in Chinese patients with wet age-related macular degeneration
D Luo, T Deng, W Yuan, H Deng, M Jin - BMC ophthalmology, 2017 - Springer
Background Age-related macular degeneration (AMD) is a leading disease associated with
blindness. It has a high incidence and complex pathogenesis. We aimed to study the …
blindness. It has a high incidence and complex pathogenesis. We aimed to study the …
Integrating genetics and metabolomics from multi-ethnic and multi-fluid data reveals putative mechanisms for age-related macular degeneration
Age-related macular degeneration (AMD) is a leading cause of blindness in older adults.
Investigating shared genetic components between metabolites and AMD can enhance our …
Investigating shared genetic components between metabolites and AMD can enhance our …
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