Metabolome-wide association study of neovascular age-related macular degeneration

MP Osborn, Y Park, MB Parks, LG Burgess, K Uppal… - PloS one, 2013 - journals.plos.org
Purpose To determine if plasma metabolic profiles can detect differences between patients
with neovascular age-related macular degeneration (NVAMD) and similarly-aged controls …

Metabolic characterization of diabetic retinopathy: An 1H-NMR-based metabolomic approach using human aqueous humor

H Jin, B Zhu, X Liu, J Jin, H Zou - Journal of Pharmaceutical and Biomedical …, 2019 - Elsevier
Patients with a long duration of diabetes mellitus (DM) usually have accompanied
complications such as diabetic retinopathy (DR), which is a leading cause of blindness and …

Challenges in age-related macular degeneration: From risk factors to novel diagnostics and prevention strategies

M Lombardo, S Serrao, G Lombardo - Frontiers in Medicine, 2022 - frontiersin.org
Age-related macular degeneration (AMD) is a chronic multifactorial eye disease
representing the primary cause of vision loss in people aged 60 years and older. The …

Effects of systemic drugs on the development and progression of age-related macular degeneration

KR Grimes, A Aloney, D Skondra, J Chhablani - Survey of Ophthalmology, 2023 - Elsevier
Age-related macular degeneration (AMD) is the leading cause of severe loss of central
vision among people over 50. The pathophysiology of the disease is multifactorial and can …

Proteomics in ocular fluids

FH Grus, SC Joachim, N Pfeiffer - PROTEOMICS–Clinical …, 2007 - Wiley Online Library
The focus of this article is to review recent techniques in proteomic analysis of ocular fluids.
These fluids include tears, aqueous humor, and vitreous, they will also be compared to …

Recent developments in age-related macular degeneration: a review

WM Al-Zamil, SA Yassin - Clinical interventions in aging, 2017 - Taylor & Francis
Background Visual impairment in elderly people is a considerable health problem that
significantly affects quality of life of millions worldwide. The magnitude of this issue is …

Signaling lipids as diagnostic biomarkers for ocular surface cicatrizing conjunctivitis

A Di Zazzo, W Yang, M Coassin, A Micera… - Journal of Molecular …, 2020 - Springer
Metabolomics has been applied to diagnose diseases, predict disease progression, and
design therapeutic strategies in various areas of medicine. However, it remains to be …

Metabolomics in retinal diseases: an update

X Li, S Cai, Z He, J Reilly, Z Zeng, N Strang, X Shu - Biology, 2021 - mdpi.com
Simple Summary Visual loss and blindness caused by retinal disease has a significant
negative effect on the quality of life of many adults and children, and as a result has become …

Is age‐related macular degeneration a manifestation of systemic disease? New prospects for early intervention and treatment

CMG Cheung, TY Wong - Journal of internal medicine, 2014 - Wiley Online Library
Age‐related macular degeneration (AMD) is a common vision‐threatening condition
affecting the elderly. AMD shares common risk factors and processes, including vascular …

[HTML][HTML] Multiplex immunoassay analysis of biomarkers in clinically accessible quantities of human aqueous humor

RK Sharma, AT Rogojina, KV Chalam - Molecular vision, 2009 - ncbi.nlm.nih.gov
Purpose Aqueous humor is intimately related to the cells of the anterior and posterior
chambers, which affect its composition. Aqueous analysis provides useful information …