Abstract Background α-Synuclein (α-Syn), a pathological hallmark of Parkinson's disease
(PD), has been recognized to induce the production of interleukin-1β in a process that …

Synucleinopathies such as Parkinson's disease (PD) are hallmarked by α‐synuclein (α‐syn)
pathology and neuroinflammation. This neuroinflammation involves activated microglia with …

Microglial inflammation is identified as a key process associated with Parkinson's disease
(PD) pathogenesis. Our previous study showed that miR‐29c‐3p (miR‐29c) exhibited anti …

Accumulating evidences suggest that neuroinflammation is a pathological hallmark of
Parkinson's disease (PD), a neurodegenerative disorder characterized by loss of …

Parkinson's disease (PD) is neurodegenerative dyskinesia characterized by loss of
dopaminergic neurons in the substantia nigra pars compacta (SNpc). Although …

The nucleotide oligomerization domain (NOD)-like receptor (NLR) pyrin domain-containing
protein 1 (NLRP1) inflammasome has been shown to contribute to brain injury after ischemic …

According to emerging studies, the excessive activation of microglia and the subsequent
release of pro-inflammatory cytokines play important roles in the pathogenesis and …

Parkinson's disease (PD) is the second most common age-related neurodegenerative
disorder and is characterized by the formation of cellular inclusions inside neurons that are …

Parkinson's disease (PD) is the second most common neurodegenerative disease, with two
main pathological features: misfolded α-synuclein protein accumulation and …

Background Parkinson's disease (PD) is characterized by the loss of nigral dopaminergic
neurons leading to impaired striatal dopamine signaling, α-synuclein-(α-syn-) rich …