Androgen receptor (AR) is a steroid receptor transcriptional factor for testosterone and
dihydrotestosterone consisting of four main domains, the N-terminal domain, DNA-binding …

Abstract In the United States, prostate cancer (PCa) is the most commonly diagnosed non-
cutaneous cancer in males and the second leading cause of cancer-related death for men …

Prostate cancer is the most frequently diagnosed non-cutaneous tumor of men in Western
countries. While surgery is often successful for organ-confined prostate cancer, androgen …

Few effective therapies exist for the treatment of castration-resistant prostate cancer (CRPC).
Recent evidence suggests that CRPC may be caused by augmented androgen/androgen …

The androgen/androgen receptor axis in prostate cancer : Current Opinion in Oncology The
androgen/androgen receptor axis in prostate cancer : Current Opinion in Oncology Log in or …

Androgen receptor (AR), a ligand-dependent nuclear transcription factor and a member of
steroid hormone receptor family, plays an important role in prostate organogenesis by …

PURPOSE: Androgen receptor (AR) is expressed in the majority of human prostate cancers.
For a better understanding of prostate carcinoma events it is necessary to present findings …

The role of the androgen receptor (AR) signaling axis in the progression of prostate cancer
is a cornerstone to our understanding of the molecular mechanisms causing castration …

Prostate cancer (PC) cells express the androgen receptor (AR) and need the presence of
androgens to survive. Androgen suppression is the gold standard first-line therapy for …

Since the original observations of Huggins and Hodges that prostate cancers are androgen
dependent, androgen ablation therapy has been the gold standard for the treatment of …