Genomic landscape of pheochromocytoma and paraganglioma

I Jochmanova, K Pacak - Trends in cancer, 2018 - cell.com
Recent comprehensive molecular analysis allowed the identification of unique molecular
signatures in pheochromocytomas (PHEOs) and paragangliomas (PGLs). Here we …

[HTML][HTML] Comprehensive molecular characterization of pheochromocytoma and paraganglioma

L Fishbein, I Leshchiner, V Walter, L Danilova… - Cancer cell, 2017 - cell.com
We report a comprehensive molecular characterization of pheochromocytomas and
paragangliomas (PCCs/PGLs), a rare tumor type. Multi-platform integration revealed that …

New perspectives on pheochromocytoma and paraganglioma: toward a molecular classification

J Crona, D Taïeb, K Pacak - Endocrine reviews, 2017 - academic.oup.com
A molecular biology–based taxonomy has been proposed for pheochromocytoma and
paraganglioma (PPGL). Data from the Cancer Genome Atlas revealed clinically relevant …

Rethinking pheochromocytomas and paragangliomas from a genomic perspective

LJ Castro-Vega, C Lepoutre-Lussey… - Oncogene, 2016 - nature.com
Pheochromocytomas (PCC) and paragangliomas (PGL) are rare neuroendocrine tumors of
neural crest origin. These tumors are caused by germline or somatic mutations in known …

Pheochromocytoma and paraganglioma pathogenesis: learning from genetic heterogeneity

PLM Dahia - Nature Reviews Cancer, 2014 - nature.com
The neuroendocrine tumours pheochromocytomas and paragangliomas carry the highest
degree of heritability in human neoplasms, enabling genetic alterations to be traced to …

An update on the genetics of paraganglioma, pheochromocytoma, and associated hereditary syndromes

AP Gimenez-Roqueplo, PL Dahia… - Hormone and …, 2012 - thieme-connect.com
Pheochromocytomas (PCCs) and paragangliomas (PGLs) are catecholamine-secreting
tumors of neural crest origin. Once collectively known as the '10% tumor', based on the …

Multi-omics analysis defines core genomic alterations in pheochromocytomas and paragangliomas

LJ Castro-Vega, E Letouzé, N Burnichon… - Nature …, 2015 - nature.com
Abstract Pheochromocytomas and paragangliomas (PCCs/PGLs) are neural crest-derived
tumours with a very strong genetic component. Here we report the first integrated genomic …

The genomic landscape of phaeochromocytoma

A Flynn, D Benn, R Clifton‐Bligh… - The Journal of …, 2015 - Wiley Online Library
Abstract Phaeochromocytomas (PCCs) and paragangliomas (PGLs) are rare neural crest‐
derived tumours originating from adrenal chromaffin cells or extra‐adrenal sympathetic and …

[HTML][HTML] New insights on the pathogenesis of paraganglioma and pheochromocytoma

V Kantorovich, K Pacak - F1000Research, 2018 - ncbi.nlm.nih.gov
Abstract Pheochromocytomas (PCCs) and paragangliomas (PGLs) are rare chromaffin cell
tumors (PPGLs) that at times raise significant challenges in clinical recognition, diagnosis …

Genetic bases of pheochromocytoma and paraganglioma

A Cascón, B Calsina, M Monteagudo… - Journal of …, 2023 - jme.bioscientifica.com
The genetics of pheochromocytoma and paraganglioma (PPGL) has become increasingly
complex over the last two decades. The list of genes involved in the development of these …