In recent years, the peptide drug discovery field has shown a high level of dynamism, with
hundreds of academic groups working on this topic, the creation of new peptide-focused …

Peptides as ‘Drugs’: The Journey so Far | SpringerLink Skip to main content Advertisement
SpringerLink Log in Menu Find a journal Publish with us Search Cart 1.Home 2.International …

The first synthetic peptide was prepared by Emil Fischer a century ago, but the medicinal
use of synthetic peptides started after the Second World War, and only when peptides could …

The analysis of these peptides by therapeutic categories is an indication of the versatility of
peptides to tackle a large number of biochemical transgressions. Thus, boceprevir and …

The suite of currently used drugs can be divided into two categories–traditional 'small
molecule'drugs with typical molecular weights of< 500 Da but with oral bioavailability, and …

Highlights•We provide a SWOT analysis of peptide therapeutics and discuss commercial
aspects.•We comment on emerging peptide technologies and cell-penetrating peptides.• …

The decreasing number of approved drugs produced by the pharmaceutical industry, which
has been accompanied by increasing expenses for R&D, demands alternative approaches …

Over the past decade, peptide drug discovery has experienced a revival of interest and
scientific momentum, as the pharmaceutical industry has come to appreciate the role that …

With the number of small molecule-based drug candidates in clinical trials and approved
drugs for the market decreasing, scientists from the pharmaceutical industry and academia …

Highlights•A comprehensive compilation and analysis of FDA approved and under clinical
trials peptide-based therapeutics.•Clinical trial peptides pipeline analysis reveals emerging …