Ceacam1 deletion causes vascular alterations in large vessels
SM Najjar, KJ Ledford, SL Abdallah… - American Journal …, 2013 - journals.physiology.org
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) promotes hepatic
insulin clearance and endothelial survival. However, its role in the morphology of …
insulin clearance and endothelial survival. However, its role in the morphology of …
Insulin sensitivity is retained in mice with endothelial loss of carcinoembryonic antigen cell adhesion molecule 1
HT Muturi, SS Khuder, HE Ghadieh, EL Esakov, H Noh… - Cells, 2021 - mdpi.com
CEACAM1 regulates endothelial barrier integrity. Because insulin signaling in extrahepatic
target tissues is regulated by insulin transport through the endothelium, we aimed at …
target tissues is regulated by insulin transport through the endothelium, we aimed at …
Reduced hepatic carcinoembryonic antigen-related cell adhesion molecule 1 level in obesity
G Heinrich, HT Muturi, K Rezaei, QY Al-Share… - Frontiers in …, 2017 - frontiersin.org
Impairment of insulin clearance is being increasingly recognized as a critical step in the
development of insulin resistance and metabolic disease. The carcinoembryonic antigen …
development of insulin resistance and metabolic disease. The carcinoembryonic antigen …
[HTML][HTML] Liver-specific rescuing of CEACAM1 reverses endothelial and cardiovascular abnormalities in male mice with null deletion of Ceacam1 gene
L Russo, HT Muturi, HE Ghadieh, AM Wisniewski… - Molecular …, 2018 - Elsevier
Objective Mice with global null mutation of Ceacam1 (Cc1−/−), display impairment of insulin
clearance that causes hyperinsulinemia followed by insulin resistance, elevated hepatic de …
clearance that causes hyperinsulinemia followed by insulin resistance, elevated hepatic de …
Forced hepatic overexpression of CEACAM1 curtails diet-induced insulin resistance
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) regulates insulin
sensitivity by promoting hepatic insulin clearance. Liver-specific inactivation or global null …
sensitivity by promoting hepatic insulin clearance. Liver-specific inactivation or global null …
Liver-specific reconstitution of CEACAM1 reverses the metabolic abnormalities caused by its global deletion in male mice
L Russo, HT Muturi, HE Ghadieh, SS Ghanem… - Diabetologia, 2017 - Springer
Aims/hypothesis The carcinoembryonic antigen-related cell adhesion molecule 1
(CEACAM1) promotes insulin clearance. Mice with global null mutation (Cc1−/−) or with liver …
(CEACAM1) promotes insulin clearance. Mice with global null mutation (Cc1−/−) or with liver …
Carcinoembryonic antigen-related cell adhesion molecule 1: a link between insulin and lipid metabolism
AM DeAngelis, G Heinrich, T Dai, TA Bowman… - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—Liver-specific inactivation of carcinoembryonic antigen-related cell adhesion
molecule 1 (CEACAM1) by a dominant-negative transgene (l-SACC1 mice) impaired insulin …
molecule 1 (CEACAM1) by a dominant-negative transgene (l-SACC1 mice) impaired insulin …
Carcinoembryonic antigen-related cell adhesion molecule 2 controls energy balance and peripheral insulin action in mice
G Heinrich, S Ghosh, AM DeAngelis… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: The carcinoembryonic antigen-related cell adhesion molecule 1
(CEACAM1) is a transmembrane glycoprotein with pleotropic functions, including clearance …
(CEACAM1) is a transmembrane glycoprotein with pleotropic functions, including clearance …
Role for hepatic CEACAM1 in regulating fatty acid metabolism along the adipocyte-hepatocyte axis [S]
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) regulates insulin
sensitivity by promoting hepatic insulin clearance and mediating suppression of fatty acid …
sensitivity by promoting hepatic insulin clearance and mediating suppression of fatty acid …
The CEACAM1 expression is decreased in the liver of severely obese patients with or without diabetes
W Lee - Diagnostic pathology, 2011 - Springer
Background Type 2 diabetes is mainly caused by insulin resistance. The carcinoembryonic
antigen-related cell adhesion molecule 1 (CEACAM1) is an important candidate for causing …
antigen-related cell adhesion molecule 1 (CEACAM1) is an important candidate for causing …