Comparison of follicular T helper cells, monocytes, and T cells priming between newly diagnosed and rituximab-treated MS patients and healthy controls

S Yahyazadeh, N Esmaeil… - Research in …, 2022 - journals.lww.com
Background and purpose: The use of anti-CD20 monoclonal antibodies like rituximab (RTX)
to deplete B cells has practical therapeutic implications in multiple sclerosis (MS) patients …

Imbalance of circulating Tfr/Tfh ratio in patients with rheumatoid arthritis

X Wang, C Yang, F Xu, L Qi, J Wang, P Yang - Clinical and experimental …, 2019 - Springer
Follicular helper T (Tfh) cells and follicular regulatory T (Tfr) cells are critical for the
development and maintenance of germinal center and humoral immune responses …

Characterization of a new regulatory CD4+ T cell subset in primary Sjögren's syndrome

A Alunno, MG Petrillo, G Nocentini, O Bistoni… - …, 2013 - academic.oup.com
Abstract Objective. CD4+ CD25lowGITR+ T lymphocytes expressing FoxP3 and showing
regulatory function have been recently described in healthy donors (HD). The objective of …

Analysis of gene expression and TCR/B cell receptor profiling of immune cells in primary Sjögren's syndrome by single-cell sequencing

X Hou, X Hong, M Ou, S Meng, T Wang… - The Journal of …, 2022 - journals.aai.org
Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease that is estimated to
affect 35 million people worldwide and is characterized by lymphocytic infiltration, elevated …

Elevated circulating T cell subsets and cytokines expression in patients with rheumatoid arthritis

H Zhou, B Hu, Z Zhaopeng, J Liu, Q Zhong, Y Fan… - Clinical …, 2019 - Springer
Objective This study aimed to assess the role of different subsets of circulating follicular
helper T cells (Tfh), central memory (TCM), effector memory (TEM), Naïve T, chemokines …

Elevated level of circulating CD4+Helios+FoxP3+ cells in primary Sjogren's syndrome patients

C Liu, Z Guan, L Zhao, Y Song… - Modern Rheumatology, 2017 - academic.oup.com
Objective: This study was designed to investigate the expression of regulatory T cells in
primary Sjögren's Syndrome (pSS) and to evaluate the clinical role of CD4+ Helios+ FoxP3+ …

Aberrant signaling of immune cells in Sjögren's syndrome patient subgroups upon interferon stimulation

I Sarkar, R Davies, AK Aarebrot, SM Solberg… - Frontiers in …, 2022 - frontiersin.org
Background Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease,
characterized by mononuclear cell infiltrates in the salivary and lacrimal glands, leading to …

FoxP3+CXCR5+CD4+ T cell frequencies are increased in peripheral blood of patients with primary Sjögren's syndrome

M Ivanchenko, LA Aqrawi, A Björk… - Clinical & …, 2019 - academic.oup.com
We recently explored the expression of CXCR5 on T and B cells from peripheral blood of
patients with primary Sjögren's syndrome (SS). Here we investigated the frequency of …

IL-10-producing regulatory B cells restrain the T follicular helper cell response in primary Sjögren's syndrome

X Lin, X Wang, F Xiao, K Ma, L Liu, X Wang… - Cellular & molecular …, 2019 - nature.com
Increased numbers of T follicular helper (Tfh) cells have been implicated in the development
of autoimmune diseases including primary Sjögren's syndrome (pSS), but how the Tfh cell …

Co-culture system of human salivary gland epithelial cells and immune cells from primary Sjögren's syndrome patients: an in vitro approach to study the effects of …

S Lisi, M Sisto, M D'Amore… - International …, 2015 - academic.oup.com
Primary Sjögren's syndrome (pSS) is a chronic autoimmune disorder of the exocrine glands
with associated lymphocytic infiltrates in the affected glands. Dryness of the mouth and eyes …