Follicular T helper (Tfh) cells have a crucial role in regulating immune responses within
secondary lymphoid follicles by directing B cell differentiation towards memory B cells and …

Primary Sjögren's syndrome (pSS) is a chronic autoimmune disorder affecting exocrine
glands of the body, prevalently lacrimal and salivary glands. The pSS pathogenesis has …

Regulatory T cells (Tregs) serve an important role in the pathogenesis of rheumatoid arthritis
(RA) by regulating autoimmunity and inflammation. Humans and mice contain inducible T …

Abstract Objectives Whether naive CD4+ T cells are dysregulated and associated with the
overactivation of CD4+ T cells in primary SS (pSS) remains unclear. We aimed to explore …

Primary Sjögren's syndrome (pSS) is an autoimmune exocrinopathy characterized by
chronic inflammation and destruction of the salivary and lacrimal glands. B-and T …

Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease associated with
damage to multiple organs and glands. The most common clinical manifestations are dry …

Accumulating evidence indicates a critical role for T cells and relevant cytokines in the
pathogenesis of systemic lupus erythematosus (SLE). However, the specific contribution of T …

Objective Systemic lupus erythematosus (SLE) is a chronic and complex autoimmune
disease characterized by multiple autoantibodies, resulting in multiple organ and tissue …

Follicular helper T (Tfh) cells play a key role in driving B cell activation and differentiation
during germinal center reactions in immune responses and autoimmune development, and …

Summary 'Circulating'T follicular helper cells (Tfh), characterized by their surface
phenotypes CD4+ chemokine receptor 5 (CXCR5)+ inducible co-stimulatory molecule …