Immunoregulatory effects of dental mesenchymal stem cells on T and B lymphocyte responses in primary Sjögren's syndrome

D Genç, B Günaydın, S Sezgin, A Aladağ… - Immunotherapy, 2022 - Taylor & Francis
Background: In this article, the authors investigate the modulatory effects of dental
mesenchymal stem cells (MSCs) on lymphocyte responses in primary Sjögren's syndrome …

Increased circulating CD4+ CXCR5+ FoxP3+ follicular regulatory T cells correlated with severity of systemic lupus erythematosus patients

C Liu, D Wang, Y Song, S Lu, J Zhao… - International …, 2018 - Elsevier
As one specialized subset of regulatory T cells (Tregs), follicular regulatory T cells (TFR)
could suppress follicular helper T cells (TFH) and B cells in germinal centers to maintain …

Selective localization of T helper subsets in labial salivary glands from primary Sjögren's syndrome patients

T Maehara, M Moriyama, JN Hayashida… - Clinical & …, 2012 - academic.oup.com
The aim of this study was to investigate the initiation and progression of autoimmune
damage in the lesions of labial salivary glands (LSGs) from primary Sjögren's syndrome …

Association between IL-7 and primary Sjögren's syndrome: A single-center study and a systematic scoping review

Y Liang, Z Zhang, J Li, W Luo, T Jiang… - International …, 2022 - Elsevier
Background There is a lack of single marker reflecting systemic activity of primary Sjögren's
syndrome (pSS). Our aim is to determine the association between interleukin (IL)-7 and pSS …

Cells with regulatory function of the innate and adaptive immune system in primary Sjögren's syndrome

P Szodoray, G Papp, IF Horvath… - Clinical & …, 2009 - academic.oup.com
The aim of the present study was to describe subsets of cells with regulatory properties in
primary Sjögren's syndrome (pSS), and to correlate these cell populations with clinical …

Decreased expression of thymic stromal lymphopoietin in salivary glands of patients with primary Sjögren's syndrome is associated with increased disease activity

MR Hillen, AA Kruize, A Bikker… - Modern …, 2016 - academic.oup.com
Abstract Objectives: Thymic Stromal Lymphopoietin (TSLP) is a potent immunomodulatory
cytokine involved in Th2-and Th17-mediated immune responses in different autoimmune …

Interleukin‐7/Interferon Axis Drives T Cell and Salivary Gland Epithelial Cell Interactions in Sjögren's Syndrome

E Rivière, J Pascaud, A Virone, A Dupré… - Arthritis & …, 2021 - Wiley Online Library
Objective Primary Sjögren's syndrome (SS) is characterized by a lymphocytic infiltration of
salivary glands (SGs) and the presence of an interferon (IFN) signature. SG epithelial cells …

Circulating follicular helper T cells are increased in systemic sclerosis and promote plasmablast differentiation through the IL-21 pathway which can be inhibited by …

L Ricard, V Jachiet, F Malard, Y Ye, N Stocker… - Annals of the …, 2019 - ard.bmj.com
Objectives Systemic sclerosis (SSc) is an autoimmune disease characterised by widespread
fibrosis, microangiopathy and autoantibodies. Follicular helper T (Tfh) cells CD4+ CXCR5+ …

Association of plasmacytoid dendritic cells with B cell infiltration in minor salivary glands in patients with Sjögren's syndrome

J Zhao, S Kubo, S Nakayamada, S Shimajiri… - Modern …, 2016 - academic.oup.com
Objectives: Sjogren's syndrome (SS) is an autoimmune disease with features of both over-
production of specific autoantibodies and organ-specific disorders, mainly sialadenitis and …

[HTML][HTML] Elevated unphosphorylated STAT1 and IRF9 in T and B cells of primary sjögren's syndrome: Novel biomarkers for disease activity and subsets

J Ritter, F Szelinski, A Aue, AL Stefanski… - Journal of …, 2024 - Elsevier
Objectives Autoreactive B cells and interferon (IFN) signature are hallmarks of primary
sjögren's syndrome (pSS), but how IFN signaling pathways influence autoantibody …