Lymphocyte subpopulations in Sjögren's syndrome are distinct in anti-SSA-positive patients and related to disease activity
F Barcelos, C Martins, N Madeira, M Ângelo-Dias… - Clinical …, 2021 - Springer
Objectives Sjögren's syndrome (SjS) patients exhibit great phenotypical heterogeneity,
reinforced by the positiveness of anti-SSA antibody. We aimed to evaluate lymphocyte …
reinforced by the positiveness of anti-SSA antibody. We aimed to evaluate lymphocyte …
[PDF][PDF] Altered subgroups of regulatory T cells in patients with primary Sjögren's syndrome
JC Lin, KL Pan, CF Li, KF Lee, KY Lin, KM Lin, CY Lin - Heliyon, 2023 - cell.com
Primary Sjögren syndrome (pSS) is a systemic autoimmune inflammatory disease. Up to
now, the role of regulatory T cells (Tregs) and their subgroups in pSS is still in controversial …
now, the role of regulatory T cells (Tregs) and their subgroups in pSS is still in controversial …
Rituximab modulates IL-17 expression in the salivary glands of patients with primary Sjögren's syndrome
Objective. The aim of this study was to evaluate the role of rituximab (RTX) in modulating the
expression of the IL-17/IL-23 pathway in the salivary glands (SGs) of patients with primary …
expression of the IL-17/IL-23 pathway in the salivary glands (SGs) of patients with primary …
Is the T follicular regulatory: follicular helper T cell ratio in blood a biomarker for ectopic lymphoid structure formation in sjögren's syndrome? comment on the article by …
GM Verstappen, U Nakshbandi, E Mossel… - Arthritis & …, 2018 - Wiley Online Library
We read with great interest the recent article by Fonseca et al in which they elegantly
showed that T follicular regulatory (Tfr) cells were enriched in blood as well as in matched …
showed that T follicular regulatory (Tfr) cells were enriched in blood as well as in matched …
High-content multimodal analysis supports the IL-7/IL-7 receptor axis as a relevant therapeutic target in primary Sjögren's syndrome
E Desvaux, P Hemon, P Soret, C Le Dantec… - Journal of …, 2023 - Elsevier
Objective While the involvement of IL-7/IL-7R axis in pSS has been described in relation to T
cells, little is known about the contribution of this pathway in relationship with other immune …
cells, little is known about the contribution of this pathway in relationship with other immune …
[HTML][HTML] Impact of corticosteroids on the proportions of circulating Tfh cell subsets in patients with systemic lupus erythematous
M Mao, S Xu, L Lin, D Dong, M Xue, S He… - Frontiers in Medicine, 2022 - frontiersin.org
Objectives: The aim of this study was to analyze the distribution of Tfh in lupus patients, and
the effects of steroid on circulating Tfh cells of patients. Methods: Circulating Tfh cell subsets …
the effects of steroid on circulating Tfh cells of patients. Methods: Circulating Tfh cell subsets …
[HTML][HTML] Exploiting the role of T cells in the pathogenesis of Sjögren's syndrome for therapeutic treatment
Q An, J Zhao, X Zhu, B Yang, Z Wu, Y Su… - Frontiers in …, 2022 - frontiersin.org
Sjögrens syndrome (SS) is caused by autoantibodies that attack proprioceptive salivary and
lacrimal gland tissues. Damage to the glands leads to dry mouth and eyes and affects …
lacrimal gland tissues. Damage to the glands leads to dry mouth and eyes and affects …
Elevated EPSTI1 promote B cell hyperactivation through NF-κB signalling in patients with primary Sjögren's syndrome
J Sun, H Zhang, S Liu, C Lian, Z Chen… - Annals of the …, 2020 - ard.bmj.com
Background Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease
characterised by aberrant B cell hyperactivation, whose mechanism is partially understood …
characterised by aberrant B cell hyperactivation, whose mechanism is partially understood …
Increased circulating follicular Treg cells are associated with lower levels of autoantibodies in patients with rheumatoid arthritis in stable remission
C Liu, D Wang, S Lu, Q Xu, L Zhao, J Zhao… - Arthritis & …, 2018 - Wiley Online Library
Objective To examine the expression and changes in function of circulating CD 4+ CXCR 5+
FoxP3+ follicular Treg (Tfr) cells in patients with active rheumatoid arthritis (RA) and in …
FoxP3+ follicular Treg (Tfr) cells in patients with active rheumatoid arthritis (RA) and in …
Alteration of innate lymphoid cell homeostasis mainly concerns salivary glands in primary Sjögren's syndrome
L Kawka, R Felten, C Schleiss, JD Fauny… - RMD open, 2023 - rmdopen.bmj.com
Objective Innate lymphoid cells (ILCs) are a cell population implicated in the pathogenesis
of various chronic inflammatory diseases, but little is known about their role in primary …
of various chronic inflammatory diseases, but little is known about their role in primary …