It has been previously shown that the subset of human natural killer (NK) cells which
express CD8 in a homodimeric α/α form are more cytotoxic than their CD8–counterparts but …

Both T cells and natural killer (NK) cells express CD2, the target of an alternative activation
pathway that induces the proliferation of both cell types. The mitogenic response to CD2 …

Activated human natural killer (NK) cells undergo rapid apoptotic cell death after ligand
binding to the Fc receptor (CD16). We examined whether human NK cells die after …

Propriocidal regulation of T cells refers to apoptosis induced by interleukin 2 (IL-2) activation
with subsequent antigen receptor stimulation. We examined whether natural killer (NK) cells …

Abstract Monoclonal (IgG) antibodies (MAbs) directed to CD 16 molecules efficiently
induced lysis of the IgG‐binding P815 target cells. A similar effect was observed with …

In contrast to the inhibitory pathway of NK cell regulation, much less is known about
stimulatory or activation signals in NK cells. Both CD80 and CD86 function as costimulatory …

The CD27 molecule is expressed on a portion of natural killer (NK) cells as well as T and B
cells. To provide the functional capacity of CD27 molecule on NK cells, we here highly …

NK cell–mediated cytotoxicity is influenced by triggering as well as inhibitory signals. The
identifica-tion of inhibitory signals provided by MHC class I molecules has recently attracted …

The CD7 molecule, one of the earliest T-lymphocyte Ag expressed during ontogeny, has
recently been demonstrated to facilitate activation of T cells and to preferentially activate …

Human natural killer cells (NK) respond to interleukin-2 (IL-2) with augmented cytolytic
activity, cytokine secretion and cell proliferation. Here we show that IL-2 protects NK cells …