The absence of the TNF-receptor family member CD27 marks the stable acquisition of
cytolytic effector functions by both CD4+ and CD8+ T cells. We found that the majority of …

The two major functions of human natural killer (NK) cells are conventionally associated with
distinct cell subsets. Thus, cytolytic activity is mostly confined to the CD56dimCD16+ subset …

CD38, a surface glycoprotein of unrestricted lineage, is an ectoenzyme (adenosine
diphosphate [ADP] ribosyl cyclase/cyclic ADP-ribose hydrolase) that regulates cytoplasmic …

Previous work showed that administration of antigen-expressing apoptotic cells in vivo
results in antigen-specific CD8+ T-cell responses independent of Toll-like receptor …

In this report, we analyze whether CD31, also known as platelet‐endothelial cell adhesion
molecule‐1 (PECAM‐1), can transduce an outside‐in signal in human natural killer (NK) …

Bacterial products such as LPS have been shown to activate monocytes and to increase
CD14 expression, while anti-inflammatory cytokines, ie, IL-4, down-regulate CD14 …

Natural killer (NK) cells must be able to eliminate infected and transformed cells while
remaining tolerant of normal cells. NK-cell self-tolerance is thought to be maintained by self …

Natural killer (NK) cells (CD56+/CD3–) in the circulation of cancer patients were reported to
have low NK activity and undergo spontaneous apoptosis. A possible relationship between …

Abstract The T11 (CD2) antigen has been found to be an alternate pathway for antigen-
independent activation of resting T cells. T11 triggering also results in activation of NK cells …

In this study we present new differential characteristics of NK cells expressing CD56 surface
antigen in low (CD56dim) or high (CD56bright) density. In contrast to CD56bright NK cells …