Cell therapy using bone marrow stromal cells in chronic paraplegic rats: systemic or local administration?

J Vaquero, M Zurita, S Oya, M Santos - Neuroscience letters, 2006 - Elsevier
Recent studies showed the therapeutic effect of bone marrow stromal cells (BMSC) after
spinal cord injury (SCI). In the present study, we compared the effect of systemic and local …

[HTML][HTML] Visual bone marrow mesenchymal stem cell transplantation in the repair of spinal cord injury

R Zhang, C Xu, Y Liu, J Li, J Xie - Neural regeneration research, 2015 - journals.lww.com
An important factor in improving functional recovery from spinal cord injury using stem cells
is maximizing the number of transplanted cells at the lesion site. Here, we established a …

Lumbar puncture delivery of bone marrow stromal cells in spinal cord contusion: a novel method for minimally invasive cell transplantation

A Bakshi, AL Barshinger, SA Swanger… - Journal of …, 2006 - liebertpub.com
Cell transplantation as a treatment for spinal cord injury is a promising therapeutic strategy
whose effective clinical application would be facilitated by non-invasive delivery protocols …

Comparison of functional and histological outcomes after intralesional, intracisternal, and intravenous transplantation of human bone marrow-derived mesenchymal …

DA Shin, JM Kim, HI Kim, S Yi, Y Ha, DH Yoon… - Acta …, 2013 - Springer
Background Few studies have compared methods of stem cell transplantation. The aim of
the present study was to determine the optimal method of delivery of therapeutic stem cells …

Bone marrow stromal cells infused into the cerebrospinal fluid promote functional recovery of the injured rat spinal cord with reduced cavity formation

M Ohta, Y Suzuki, T Noda, Y Ejiri, M Dezawa… - Experimental …, 2004 - Elsevier
The effects of bone marrow stromal cells (BMSCs) on the repair of injured spinal cord and on
the behavioral improvement were studied in the rat. The spinal cord was injured by …

Detection of 111In-oxine-labeled bone marrow stromal cells after intravenous or intralesional administration in chronic paraplegic rats

J de Haro, M Zurita, L Ayllón, J Vaquero - Neuroscience Letters, 2005 - Elsevier
Recent studies suggested that bone marrow stromal cells (BMSC) may have a therapeutic
role in the treatment of paraplegia secondary to severe spinal cord injury (SCI). For this …

Dissemination and proliferation of neural stem cells on the spinal cord by injection into the fourth ventricle of the rat: a method for cell transplantation

H Bai, Y Suzuki, T Noda, S Wu, K Kataoka… - Journal of neuroscience …, 2003 - Elsevier
We examined the distribution of hippocampus-derived neural stem cells on the spinal cord
surface for up to 3 weeks following injection through the fourth ventricle. The injected cells …

Intravenous administration of mesenchymal stem cells derived from bone marrow after contusive spinal cord injury improves functional outcome

M Osaka, O Honmou, T Murakami, T Nonaka, K Houkin… - Brain research, 2010 - Elsevier
Transplantation of mesenchymal stem cells (MSCs) derived from bone marrow has been
shown to improve functional outcome in spinal cord injury (SCI). Systemic delivery of MSCs …

Axon growth and recovery of function supported by human bone marrow stromal cells in the injured spinal cord exhibit donor variations

B Neuhuber, BT Himes, JS Shumsky, G Gallo, I Fischer - Brain research, 2005 - Elsevier
Bone marrow stromal cells (MSC) are non-hematopoietic support cells that can be easily
derived from bone marrow aspirates. Human MSC are clinically attractive because they can …

Bone marrow stromal cells for spinal cord repair, A challenge for contemporary neurobiology

J Vaquero, M Zurita - Histology and histopathology, 2009 - digitum.um.es
In the last years, it has been reported that bone marrow stromal cells (BMSC) are able to
differentiate towards a neuronal phenotype, in vitro as well as in vivo, and consequently, the …