When tractography meets tracer injections: a systematic study of trends and variation sources of diffusion-based connectivity

DB Aydogan, R Jacobs, S Dulawa… - Brain Structure and …, 2018 - Springer
Tractography is a powerful technique capable of non-invasively reconstructing the structural
connections in the brain using diffusion MRI images, but the validation of tractograms is …

Anatomical accuracy of brain connections derived from diffusion MRI tractography is inherently limited

C Thomas, FQ Ye, MO Irfanoglu… - Proceedings of the …, 2014 - National Acad Sciences
Tractography based on diffusion-weighted MRI (DWI) is widely used for mapping the
structural connections of the human brain. Its accuracy is known to be limited by technical …

Limits to anatomical accuracy of diffusion tractography using modern approaches

KG Schilling, V Nath, C Hansen, P Parvathaneni… - Neuroimage, 2019 - Elsevier
Diffusion MRI fiber tractography is widely used to probe the structural connectivity of the
brain, with a range of applications in both clinical and basic neuroscience. Despite …

Diffusion MRI-based cortical connectome reconstruction: dependency on tractography procedures and neuroanatomical characteristics

MRT Sinke, WM Otte, D Christiaens, O Schmitt… - Brain Structure and …, 2018 - Springer
Diffusion MRI (dMRI)-based tractography offers unique abilities to map whole-brain
structural connections in human and animal brains. However, dMRI-based tractography …

Comparison between diffusion MRI tractography and histological tract-tracing of cortico-cortical structural connectivity in the ferret brain

C Delettre, A Messé, LA Dell, O Foubet… - Network …, 2019 - direct.mit.edu
The anatomical wiring of the brain is a central focus in network neuroscience. Diffusion MRI
tractography offers the unique opportunity to investigate the brain fiber architecture in vivo …

[HTML][HTML] TractoFlow: A robust, efficient and reproducible diffusion MRI pipeline leveraging Nextflow & Singularity

G Theaud, JC Houde, A Boré, F Rheault, F Morency… - Neuroimage, 2020 - Elsevier
Diffusion MRI tractography processing pipeline requires a large number of steps (typically
20+ steps). If parameters of these steps, number of threads, and random seed generators …

The challenge of mapping the human connectome based on diffusion tractography

KH Maier-Hein, PF Neher, JC Houde, MA Côté… - Nature …, 2017 - nature.com
Tractography based on non-invasive diffusion imaging is central to the study of human brain
connectivity. To date, the approach has not been systematically validated in ground truth …

[HTML][HTML] Microstructure informed tractography: pitfalls and open challenges

A Daducci, A Dal Palú, M Descoteaux… - Frontiers in …, 2016 - frontiersin.org
One of the major limitations of diffusion MRI tractography is that the fiber tracts recovered by
existing algorithms are not truly quantitative. Local techniques for estimating more …

[HTML][HTML] Diffusion MRI and anatomic tracing in the same brain reveal common failure modes of tractography

G Grisot, SN Haber, A Yendiki - Neuroimage, 2021 - Elsevier
Anatomic tracing is recognized as a critical source of knowledge on brain circuitry that can
be used to assess the accuracy of diffusion MRI (dMRI) tractography. However, most prior …

Towards quantitative connectivity analysis: reducing tractography biases

G Girard, K Whittingstall, R Deriche, M Descoteaux - Neuroimage, 2014 - Elsevier
Diffusion MRI tractography is often used to estimate structural connections between brain
areas and there is a fast-growing interest in quantifying these connections based on their …