An Evidence-Based Analysis of the Effect of Busulfan, Hydroxyurea, Interferon, and Allogeneic Bone Marrow Transplantation in Treating the Chronic Phase of Chronic …

RT Silver, SH Woolf, R Hehlmann… - Blood, The Journal …, 1999 - ashpublications.org
Because there are differing opinions regarding treatment of patients in the chronic phase of
chronic myeloid leukemia (CML), the American Society of Hematology convened an expert …

Chronic myeloid leukemia and interferon-α: a study of complete cytogenetic responders

F Bonifazi, A de Vivo, G Rosti, F Guilhot… - Blood, The Journal …, 2001 - ashpublications.org
Achieving a complete cytogenetic response (CCgR) is a major target in the treatment of
chronic myeloid leukemia (CML) with interferon-α (IFN-α), but CCgRs are rare. The mean …

Results of interferon-alpha therapy in patients with chronic myelogenous leukemia 60 years of age and older

J Cortes, H Kantarjian, S O'Brien, LE Robertson… - The American journal of …, 1996 - Elsevier
PURPOSE: To determine the response rate to interferon-alpha (IFN-α) in patients with
chronic myelogenous leukemia (CML) aged 60 years and older. PATIENTS AND …

Chronic myelogenous leukemia: a review

JE Cortes, M Talpaz, H Kantarjian - The American journal of medicine, 1996 - Elsevier
Chronic myelogenous leukemia (CML) is a chronic myeloproliferative disorder with an
initially chronic course lasting for 3–5 years. It eventually transforms into accelerated and …

Chronic myeloid leukemia in the elderly: long-term results from randomized trials with interferon α

U Berger, G Engelich, O Maywald, M Pfirrmann… - Leukemia, 2003 - nature.com
Chronic myeloid leukemia (CML) in older patients has not been studied well. To assess the
long-term outcome of older patients with Philadelphia-and/or BCR-ABL-positive CML, 199 …

Determinants of prognosis in late chronic-phase chronic myelogenous leukemia.

J Rodriguez, J Cortes, T Smith, S O'Brien… - Journal of clinical …, 1998 - ascopubs.org
PURPOSE Since interferon alfa (IFN-A) became an established treatment in chronic
myelogenous leukemia (CML), more patients are referred to tertiary centers in late chronic …

Outcome for patients who relapse after allogeneic bone marrow transplantation for chronic myeloid leukemia. Chronic Leukemia Working Party. European Bone …

W Arcese, JM Goldman, E D'arcangelo, A Schattenberg… - 1993 - ashpublications.org
We studied the clinical course of 130 chronic myeloid leukemia (CML) patients (89 males
and 41 females) in the European Bone Marrow Transplantation Group (EBMT) registry who …

Chronic myeloid leukemia: current treatment options

JM Goldman, BJ Druker - Blood, The Journal of the American …, 2001 - ashpublications.org
The choice of primary treatment for patients with chronic myeloid leukemia (CML) diagnosed
in chronic phase has become exceedingly difficult. There is little doubt that allogeneic stem …

Effect of prior interferon alfa therapy on the outcome of allogeneic bone marrow transplantation for chronic myelogenous leukemia.

SA Giralt, HM Kantarjian, M Talpaz, MB Rios… - Journal of clinical …, 1993 - ascopubs.org
PURPOSE To determine whether prior interferon alfa (IFN-A) treatment affects the outcome
of allogeneic bone marrow transplantation. PATIENTS AND METHODS We analyzed the …

Simultaneous homoharringtonine and interferon‐α in the treatment of patients with chronic‐phase chronic myelogenous leukemia

S O'Brien, M Talpaz, J Cortes, J Shan, FJ Giles… - Cancer, 2002 - Wiley Online Library
BACKGROUND Homoharringtonine (HHT) has antileukemic activity in patients with
Philadelphia chromosome (Ph) positive chronic myelogenous leukemia (CML) …