Current treatment of atypical hemolytic uremic syndrome

BS Kaplan, RL Ruebner, JM Spinale… - Intractable & rare …, 2014 - jstage.jst.go.jp
Tremendous advances have been made in understanding the pathogenesis of atypical
Hemolytic Uremic Syndrome (aHUS), an extremely rare disease. Insights into the molecular …

Atypical hemolytic uremic syndrome: a brief review

K Zhang, Y Lu, KT Harley, MH Tran - Hematology reports, 2017 - mdpi.com
Atypical hemolytic uremic syndrome (aHUS) is a disease characterized by the triad of
microangiopathic hemolytic anemia, thrombocytopenia and acute kidney injury. The …

Can eculizumab be discontinued in aHUS?: case report and review of the literature

T Sahutoglu, T Basturk, T Sakaci, Y Koc, E Ahbap… - Medicine, 2016 - journals.lww.com
Background: The management of atypical hemolytic uremic syndrome (aHUS) has evolved
into better control of thrombotic microangiopathy (TMA) and recovery of renal functions since …

Clinical evaluation of thrombotic microangiopathy: identification of patients with suspected atypical hemolytic uremic syndrome

YM Shen - Thrombosis Journal, 2016 - Springer
Atypical hemolytic uremic syndrome (aHUS) is a rare genetic disorder caused by defective
complement regulation resulting in thrombotic microangiopathy (TMA). Patients can present …

An update for atypical haemolytic uraemic syndrome: diagnosis and treatment. A consensus document

JM Campistol, M Arias Ballesteros, G Ariceta, M Blasco… - 2013 - digital.csic.es
[EN] Haemolytic uraemic syndrome (HUS) is a clinical entitydefined as the triad of
nonimmune haemolytic anaemia, thrombocytopenia, and acute renal failure, in which …

[HTML][HTML] A case of atypical hemolytic uremic syndrome successfully treated with eculizumab

B Thajudeen, A Sussman, E Bracamonte - Case Reports in Nephrology …, 2013 - karger.com
Atypical hemolytic uremic syndrome (aHUS) is a rare thrombotic microangiopathy (TMA)
characterized by the triad of hemolytic anemia, thrombocytopenia, and acute renal failure …

Discontinuation of eculizumab maintenance treatment for atypical hemolytic uremic syndrome: a report of 10 cases

G Ardissino, S Testa, I Possenti, F Tel… - American Journal of …, 2014 - Elsevier
Atypical hemolytic uremic syndrome (aHUS) is a life-threatening thrombotic
microangiopathy, and as many as 70% of patients with aHUS have mutations in the genes …

Atypical Hemolytic–Uremic Syndrome: A Clinical Review

A Nayer, A Asif - American journal of therapeutics, 2016 - journals.lww.com
Atypical hemolytic–uremic syndrome (HUS) is a rare life-threatening disorder characterized
by microangiopathic hemolytic anemia, thrombocytopenia, and ischemic injury to organs …

[HTML][HTML] Atypical hemolytic uremic syndrome (aHUS): treating the patient

J Laurence - Clin Adv Hematol Oncol, 2013 - hematologyandoncology.net
The 3 major thrombotic microangiopathies (TMAs) are thrombotic thrombocytopenic purpura
(TTP), atypical hemolytic uremic syndrome (aHUS), and Shiga toxin–producing Escherichia …

Eculizumab as first-line therapy for atypical hemolytic uremic syndrome

M Christmann, M Hansen, C Bergmann… - …, 2014 - publications.aap.org
Atypical hemolytic uremic syndrome (aHUS) is a genetic, life-threatening, chronic disease
that can affect patients of all ages. aHUS is caused by uncontrolled complement activation …