Experimental study of specific antitumor immunity induced by dendritic cell vaccine transfected with tumor cell total RNA in lung cancer patients
R Xiubao, L Zheng, Y JInpu, L Hong… - Zhongguo Mian yi xue …, 2004 - europepmc.org
Transfected DCs exhibited dramatically increased expression of specific membrane markers
and function-associated molecules, and were more potent in stimulating allogenous or …
and function-associated molecules, and were more potent in stimulating allogenous or …
Priming of T cells with aAd-transduced DC followed by expansion with peptide-pulsed DC significantly enhances the induction of tumor-specific CD8+ T cells …
A Tuettenberg, H Jonuleit, T Tüting, J Brück, J Knop… - Gene therapy, 2003 - nature.com
In recent years, vaccination strategies using antigen-presenting cells (APC) have been
under investigation. Antigen delivery using genetic immunization through ex vivo …
under investigation. Antigen delivery using genetic immunization through ex vivo …
[HTML][HTML] Recombinant AAV-CEA tumor vaccine in combination with an immune adjuvant breaks tolerance and provides protective immunity
JA Hensel, V Khattar, S Ponnazhagan - Molecular Therapy-Oncolytics, 2019 - cell.com
Carcinoembryonic antigen (CEA) is a human glycoprotein involved in cellular adhesion and
expressed during human fetal development. Although expression of CEA largely ceases …
expressed during human fetal development. Although expression of CEA largely ceases …
Preparation of native and amplified tumour RNA for dendritic cell transfection and generation of in vitro anti-tumour CTL responses
M Bergant, L Meden, U Repnik, V Sojar… - Immunobiology, 2006 - Elsevier
Recent research indicates that dendritic cells transfected with RNA-encoded tumour-
associated antigens (TAA) can generate potent anti-tumour immune responses in vitro and …
associated antigens (TAA) can generate potent anti-tumour immune responses in vitro and …
Induction of carcinoembryonic antigen (cea)‐specific cytotoxic t‐lymphocyte responses In vitro using autologous dendritic cells loaded with cea peptide or cea rna in …
SK Nair, S Hull, D Coleman, E Gilboa… - … journal of cancer, 1999 - Wiley Online Library
The application of dendritic cells (DC) to the active immunotherapy of cancer currently relies
on the generation of potent DC capable of presenting tumor antigens such as …
on the generation of potent DC capable of presenting tumor antigens such as …
[HTML][HTML] Whole tumor antigen vaccination using dendritic cells: comparison of RNA electroporation and pulsing with UV-irradiated tumor cells
F Benencia, MC Courrèges, G Coukos - Journal of translational medicine, 2008 - Springer
Because of the lack of full characterization of tumor associated antigens for solid tumors,
whole antigen use is a convenient approach to tumor vaccination. Tumor RNA and apoptotic …
whole antigen use is a convenient approach to tumor vaccination. Tumor RNA and apoptotic …
In vitro induction of carcinoembryonic antigen (CEA) specific cytotoxic T lymphocytes using dendritic cells pulsed with CEA peptide
MH PARK, CS LEE, MH CHO, C Han… - Journal of the …, 2005 - pesquisa.bvsalud.org
PURPOSE: Dendritic cells (DCs) are the most potent antigen-presenting cells for initiating
the T cell immune response in vivo. Recent studies have shown that active immunotherapy …
the T cell immune response in vivo. Recent studies have shown that active immunotherapy …
DNA vaccine expressing repeated carcinoembryonic antigen (CEA) 625–667 induces strong immunity in mice
D Li, S Hua, Y Fan, S Xu, X Duan, L Liu, Y Che, S Li… - Immunology letters, 2011 - Elsevier
The efficacy of immunization with DNA plasmids for single truncated carcinoembryonic
antigen (CEA) peptide or triple repeated CEA peptides in mice was evaluated. A DNA …
antigen (CEA) peptide or triple repeated CEA peptides in mice was evaluated. A DNA …
Identification of an Interferon-γ-inducible Carcinoembryonic Antigen (CEA) CD8+ T-Cell Epitope, Which Mediates Tumor Killing in CEA Transgenic Mice
J Schmitz, E Reali, JW Hodge, A Patel, G Davis… - Cancer research, 2002 - AACR
This study describes a CD8+ T-cell line specific for a MHC class I-restricted
carcinoembryonic antigen (CEA) epitope, residues 526–533, isolated from CEA transgenic …
carcinoembryonic antigen (CEA) epitope, residues 526–533, isolated from CEA transgenic …
Vaccination of colorectal cancer patients with carcinoembryonic antigen peptide-loaded dendritic cells
WJ Lesterhuis, IJ de Vries, D Schuurhuis… - Journal of Clinical …, 2005 - ascopubs.org
2544 Dendritic cells (DC) are the most potent antigen presenting cells of the immune
system, capable of inducing an effective anti-tumor immune response. They can be cultured …
system, capable of inducing an effective anti-tumor immune response. They can be cultured …