Erlotinib Versus Gemcitabine Plus Cisplatin as Neoadjuvant Treatment of Stage IIIA-N2 EGFR-Mutant Non–Small-Cell Lung Cancer (EMERGING-CTONG 1103): A …

WZ Zhong, KN Chen, C Chen, CD Gu… - Journal of clinical …, 2019 - ascopubs.org
PURPOSE To assess the benefits of epidermal growth factor receptor (EGFR) tyrosine
kinase inhibitors as neoadjuvant/adjuvant therapies in locally advanced EGFR mutation …

Erlotinib as Neoadjuvant Therapy in Stage IIIA (N2) EGFR Mutation‐Positive Non‐Small Cell Lung Cancer: A Prospective, Single‐Arm, Phase II Study

L Xiong, R Li, J Sun, Y Lou, W Zhang, H Bai… - The …, 2019 - academic.oup.com
Abstract Lessons Learned The findings of this prospective, single‐arm, phase II study
showed that neoadjuvant erlotinib was well tolerated and might improve the radical …

Phase II study of biomarker-guided neoadjuvant treatment strategy for IIIA-N2 non-small cell lung cancer based on epidermal growth factor receptor mutation status

W Zhong, X Yang, H Yan, X Zhang, J Su… - Journal of Hematology & …, 2015 - Springer
Background Neoadjuvant erlotinib and customized adjuvant therapy are appealing but
controversial. The purpose of this study was to evaluate the role of biomarker-guided …

CTONG1104: adjuvant gefitinib versus chemotherapy for resected N1-N2 NSCLC with EGFR mutation—final overall survival analysis of the randomized phase III trial …

YL Wu, W Zhong, Q Wang, W Mao, ST Xu, L Wu… - 2020 - ascopubs.org
9005 Background: ADJUVANT-CTONG1104, a randomized phase 3 trial showed adjuvant
gefitinib treatment significantly improved disease-free survival (DFS) vs standard doublet …

Erlotinib versus vinorelbine plus cisplatin as adjuvant therapy in Chinese patients with stage IIIA EGFR mutation-positive non-small-cell lung cancer (EVAN): a …

D Yue, S Xu, Q Wang, X Li, Y Shen, H Zhao… - The Lancet …, 2018 - thelancet.com
Background Adjuvant chemotherapy after radical resection of stage IIIA non-small-cell lung
cancer (NSCLC) has quite poor outcomes. We aimed to investigate whether adjuvant …

Gefitinib versus vinorelbine plus cisplatin as adjuvant treatment for stage II-IIIA (N1-N2) EGFR-mutant NSCLC: final overall survival analysis of CTONG1104 phase III …

WZ Zhong, Q Wang, WM Mao, ST Xu, L Wu… - Journal of clinical …, 2021 - ascopubs.org
PURPOSE ADJUVANT-CTONG1104 (ClinicalTrials. gov identifier: NCT01405079), a
randomized phase III trial, showed that adjuvant gefitinib treatment significantly improved …

Tumor response and toxicity of neoadjuvant erlotinib in patients with early-stage non–small-cell lung cancer

EE Schaake, I Kappers, HE Codrington… - Journal of clinical …, 2012 - ascopubs.org
Purpose The development of targeted therapy has introduced new options to improve
treatment outcome in selected patients. The objective of this prospective study was to …

Randomized Phase III Study of Gefitinib Versus Cisplatin Plus Vinorelbine for Patients With Resected Stage II-IIIA Non–Small-Cell Lung Cancer With EGFR Mutation …

H Tada, T Mitsudomi, T Misumi, K Sugio… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE To investigate the efficacy of gefitinib as an adjuvant therapy for non–small-cell
lung cancer patients with EGFR mutation. PATIENTS AND METHODS IMPACT …

Pemetrexed-carboplatin adjuvant chemotherapy with or without gefitinib in resected stage IIIA-N2 non-small cell lung cancer harbouring EGFR mutations: a …

N Li, W Ou, X Ye, HB Sun, L Zhang, Q Fang… - Annals of surgical …, 2014 - Springer
Background Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) show
great efficacy in patients with advanced non-small cell lung cancer (NSCLC) with EGFR …

Neoadjuvant EGFR-TKI therapy for EGFR-mutant NSCLC: a systematic review and pooled analysis of five prospective clinical trials

L Sun, YJ Guo, J Song, YR Wang, SL Zhang… - Frontiers in …, 2021 - frontiersin.org
Purpose The role of neoadjuvant epidermal growth factor receptor (EGFR)-tyrosine kinase
inhibitor (TKI) targeted therapy for patients with EGFR-mutant non-small cell lung cancer …