[HTML][HTML] Enrichment of phosphatidylinositols with specific acyl chains
There are six major species of phospholipids in eukaryotes, each of which plays unique
structural and functional roles. One species, phosphatidylinositol (PI) only contributes about …
structural and functional roles. One species, phosphatidylinositol (PI) only contributes about …
[HTML][HTML] PIP2 and PIP3: complex roles at the cell surface
MP Czech - Cell, 2000 - cell.com
Phosphatidylinositol (4, 5)-bisphosphate (PIP2) and phosphatidylinositol (3, 4, 5)-
trisphosphate (PIP3) represent less than 1% of membrane phospholipids, yet they function …
trisphosphate (PIP3) represent less than 1% of membrane phospholipids, yet they function …
Phosphoinositide‐metabolizing enzymes at the interface between membrane traffic and cell signalling
M Krauß, V Haucke - EMBO reports, 2007 - embopress.org
Phosphoinositides (PIs) have long been known to have important roles in cell signalling.
During the past decade, it has become clear that these lipids also act as constitutive signals …
During the past decade, it has become clear that these lipids also act as constitutive signals …
[HTML][HTML] MapPIng PI inside cells brings new light to polyphosphoinositide biology
G Drin - Journal of Cell Biology, 2020 - rupress.org
It is unclear how phosphatidylinositol (PI), the precursor of polyphosphoinositides, is
distributed within cell membranes. Pemberton et al.(2020. J. Cell. Biol. https://doi …
distributed within cell membranes. Pemberton et al.(2020. J. Cell. Biol. https://doi …
A thematic series on lipid signaling: prologue
Y Nozawa - The journal of biochemistry, 2002 - jstage.jst.go.jp
In 1925, Gorter and Grendel proposed the first structural model of the biological membrane
as a rigid lipid bilayer sandwiched between protein sheets. Since then, various modified …
as a rigid lipid bilayer sandwiched between protein sheets. Since then, various modified …
Lipid transfer proteins and instructive regulation of lipid kinase activities: Implications for inositol lipid signaling and disease
MG Lete, A Tripathi, V Chandran, VA Bankaitis… - Advances in biological …, 2020 - Elsevier
Cellular membranes are critical platforms for intracellular signaling that involve complex
interfaces between lipids and proteins, and a web of interactions between a multitude of lipid …
interfaces between lipids and proteins, and a web of interactions between a multitude of lipid …
Analysis of phosphatidic acid binding and regulation of PIPKI in vitro and in intact cells
Abstract Phosphatidylinositol 4, 5-bisphosphate [PI (4, 5) P2] is a lipid second messenger
that regulates a wide array of essential cellular events, such as signal transduction, vesicle …
that regulates a wide array of essential cellular events, such as signal transduction, vesicle …
Determinants of molecular specificity in phosphoinositide regulation: Phosphatidylinositol (4, 5)-bisphosphate (PI (4, 5) P2) is the endogenous lipid regulating TRPV1
RM Klein, CA Ufret-Vincenty, L Hua… - Journal of biological …, 2008 - ASBMB
Once thought of as simply an oily barrier that maintains cellular integrity, lipids are now
known to play an active role in a large variety of cellular processes. Phosphoinositides are of …
known to play an active role in a large variety of cellular processes. Phosphoinositides are of …
[图书][B] Phosphoinositides I: Enzymes of synthesis and degradation
Phosphoinositides play a major role in cellular signaling and membrane organization.
During the last three decades we have learned that enzymes turning over phosphoinositides …
During the last three decades we have learned that enzymes turning over phosphoinositides …