BackgroundAttaining smart drug release and preventing premature leakage throughout the
delivery process are crucial factors that essential to take into account in the design of …

Background Improving anti-cancer drug delivery performance can be achieved through
designing smart and targeted drug delivery systems (DDSs). For this aim, it is important to …

To achieve drug targeting and on-demand releasing, surface functionalization plays a
critical role in fabricating potential mesoporous silica nanoparticles (MSNs) toward tumor …

Synergistic therapy involving two or more therapeutic agents with different anticancer
mechanisms represents a promising approach to eradicate chemotherapy-refractory …

Conventional cancer chemotherapy is often associated with toxicity issues. Thus, new drug
delivery systems (DDSs) are developed as alternatives owing to their potential to selectively …

In the field of nanomedicine, drug-loaded nanocarriers that integrate nanotechnology and
chemotherapeutics are widely used to achieve synergistic therapeutic effects. Here, we …

In recent years, mesoporous silica nanoparticles (MSNs) have been used as effective
supports for the development of controlled-release nanodevices that are able to act as …

This dissertation delves into the innovative application of mesoporous silica nanoparticles
(MSNs) for targeted drug delivery in colorectal cancer (CRC), one of the most prevalent and …

Engineering multifunctional nanocarriers for targeted drug delivery shows promising
potentials to revolutionize the cancer chemotherapy. Simple methods to optimize …

Tumor-targeted delivery and controlled release of antitumor drugs are promising strategies
for increasing chemotherapeutic efficacy and reducing adverse effects. Although …