A summary of the biological processes, disease-associated changes, and clinical applications of DNA methylation

GB Andersen, J Tost - DNA Methylation Protocols, 2018 - Springer
DNA methylation at cytosines followed by guanines, CpGs, forms one of the multiple layers
of epigenetic mechanisms controlling and modulating gene expression through chromatin …

[引用][C] DNA methylation in the mammalian genome

M Paulsen, S Tierling, J Walter - Epigenetics, 2008 - Caister Academic Press Norfolk (UK)

[PDF][PDF] New insights on the role of DNA methylation from a global view

K Meier, F Recillas-Targa - Front Biosci (Landmark Ed), 2017 - article.imrpress.com
In mammals, DNA methylation is a crucial epigenetic modification with key functions during
development. Cellular processes that are regulated by DNA methylation comprise X …

DNA methylation and chromatin–unraveling the tangled web

KD Robertson - Oncogene, 2002 - nature.com
Methylation of cytosines within the CpG dinucleotide by DNA methyltransferases is involved
in regulating transcription and chromatin structure, controlling the spread of parasitic …

DNA methylation and epigenotypes

R Holliday - Biochemistry (Moscow), 2005 - Springer
The science of epigenetics is the study of all those mechanisms that control the unfolding of
the genetic program for development and determine the phenotypes of differentiated cells …

DNA methylation and cancer

RL Momparler, V Bovenzi - Journal of cellular physiology, 2000 - Wiley Online Library
The methylation of DNA is an epigenetic modification that can play an important role in the
control of gene expression in mammalian cells. The enzyme involved in this process is DNA …

The meaning of the methylation of genomic DNA in the regulation of gene expression levels.

A Popiela, G Keith, A Borzecki, G Popiela… - European journal of …, 2004 - europepmc.org
Methylation of genomic DNA is one of the major mechanisms that deactivates genes and
regulates their tissue-specific transcription levels. Its patterns are based on clonal …

Epigenetics and Cancer DNA Methylation

S Ropero, M Esteller - Epigenetics in biology and medicine, 2008 - taylorfrancis.com
Cancer can be defined in many different ways, depending on the area in which the disease
is studied, and it can be understood to encompass a group of about 100 different and …

DNA methylation changes in cancer

M Toyota, E Yamamoto - Progress in molecular biology and translational …, 2011 - Elsevier
DNA methylation of CpG islands, together with deacetylation of histone and methylation of
histone H3 lysines 9 and 27 (K9/K27), can lead to silencing of tumor-suppressor genes. The …

Enzymatic DNA methylation is an epigenetic control for genetic functions of the cell

BF Vanyushin - Biochemistry (Moscow), 2005 - Springer
In eukaryotic cells nuclear DNA is subjected to enzymatic methylation resulting in formation
of 5-methylcytosine residues mainly in CG and CNG sequences. In plants and animals, this …