In eukaryotic cells nuclear DNA is subjected to enzymatic methylation resulting in formation
of 5-methylcytosine residues mainly in CG and CNG sequences. In plants and animals, this …

Background Research in the last decade has confirmed the importance of epigenetic
processes for the onset, development, and treatment of cancer. Next generation sequencing …

DNA methylation is an essential part of the epigenome chromatin modification network,
which also comprises several covalent histone protein post-translational modifications. All …

In eukaryotic cells, nuclear DNA is subject to enzymatic methylation with the formation of 5-
methylcytosine residues, mostly within the CG and CNG sequences. In plants and animals …

Cytosine methylation is a post-replicative DNA modification associated with transcriptional
repression. This process consists in covalent addition of a methyl group to cytosine within …

DNA methylation is the most important epigenetic modification involved in the regulation of
transcription, imprinting, establishment of X-inactivation, and the formation of a chromatin …

DNA methylation, the addition of a methyl group to the carbon-5 position of cytosine
residues, is the only common covalent modification of human DNA and occurs almost …

Modern approaches for studies on genome functioning include investigation of its epigenetic
regulation. Methylation of cytosines in CpG dinucleotides is an inherited epigenetic …

Epigenetics is the science of the heritable properties of the organism that are not associated
with changes in the DNA nucleotide sequence but can be indirectly encoded in the genome …

DNA methylation regulates many cellular processes, including embryonic development,
transcription, chromatin structure, X-chromosome inactivation, genomic imprinting and …