[HTML][HTML] Genome-wide methods for investigating long noncoding RNAs

M Cao, J Zhao, G Hu - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Long noncoding RNAs (lncRNAs) are large RNA transcripts that do not code for proteins but
exert their effects in the form of RNA. To date many thousands of lncRNAs have been …

[HTML][HTML] The research strategies for probing the function of long noncoding RNAs

B Yan, ZH Wang, JT Guo - Genomics, 2012 - Elsevier
Long noncoding RNAs (lncRNAs) represent a new frontier in molecular genetics and
molecular biology. They have a tremendous potential for advancing our comprehensive …

The specificity of long noncoding RNA expression

BS Gloss, ME Dinger - Biochimica et Biophysica Acta (BBA)-Gene …, 2016 - Elsevier
Over the last decade, long noncoding RNAs (lncRNAs) have emerged as a fundamental
molecular class whose members play pivotal roles in the regulation of the genome. The …

Long noncoding RNAs: lincs between human health and disease

ZH Kwok, Y Tay - Biochemical Society Transactions, 2017 - portlandpress.com
Long noncoding RNAs (lncRNAs) represent one of the largest classes of transcripts and are
highly diverse in terms of characteristics and functions. Advances in high-throughput …

Long noncoding RNAs: insights from biological features and functions to diseases

X Li, Z Wu, X Fu, W Han - Medicinal research reviews, 2013 - Wiley Online Library
Over the past decade, genome‐wide transcriptomic studies have shown that the mammalian
genome is pervasively transcribed and produces many thousands of transcriptomes without …

Long non-coding RNAs: challenges for diagnosis and therapies

Y Sánchez, M Huarte - Nucleic acid therapeutics, 2013 - liebertpub.com
Long non-coding RNAs (lncRNAs) have emerged as one of the largest and more diverse
classes of cellular transcripts. The growing evidence suggests that lncRNAs are key …

Strategies to identify long noncoding RNAs involved in gene regulation

C Lee, N Kikyo - Cell & Bioscience, 2012 - Springer
Long noncoding RNAs (lncRNAs) have been detected in nearly every cell type and found to
be fundamentally involved in many biological processes. The characterization of lncRNAs …

Long noncoding RNAs: fresh perspectives into the RNA world

L Yang, JE Froberg, JT Lee - Trends in biochemical sciences, 2014 - cell.com
Large-scale mapping of transcriptomes has revealed significant levels of transcriptional
activity within both unannotated and annotated regions of the genome. Interestingly, many of …

Functional annotation of lncRNA in high-throughput screening

CW Yip, DM Sivaraman, AV Prabhu… - Essays in …, 2021 - portlandpress.com
Recent efforts on the characterization of long non-coding RNAs (lncRNAs) revealed their
functional roles in modulating diverse cellular processes. These include pluripotency …

LncBook: a curated knowledgebase of human long non-coding RNAs

L Ma, J Cao, L Liu, Q Du, Z Li, D Zou… - Nucleic acids …, 2019 - academic.oup.com
Long non-coding RNAs (lncRNAs) have significant functions in a wide range of important
biological processes. Although the number of known human lncRNAs has dramatically …