Interleukin (IL)-6 is a pro-inflammatory cytokine that produces multifunctional effects.
Deregulated IL-6 production and signaling are associated with chronic inflammatory …

IL-6 activates various cell types carrying the membrane bound IL-6R (classical IL-6
signaling) as well as IL-6R− gp130+ cells via the soluble IL-6R (IL-6 trans-signaling). IL-6 …

Abstract Interleukin-6 (IL-6) is a pivotal cytokine with a diverse repertoire of physiological
functions that include regulation of immune cell proliferation and differentiation …

The classification of interleukin-6 (IL-6) as a pro-inflammatory cytokine undervalues the
biological impact of this cytokine in health and disease. With broad activities affecting the …

Background: IL-6, a glycoprotein composed of 212 amino acids in human, has a wide range
of biological activity, including regulation of immune response, support of hematopoiesis …

Abstract Interleukin-6 (IL-6) is a pleiotropic pro-inflammatory cytokine. Its deregulation is
associated with chronic inflammation, and multifactorial auto-immune disorders. It mediates …

The incidence and diversity of chronic inflammatory diseases is increasing worldwide.
However, the complexity of clinical symptoms has made it difficult to develop therapies that …

Interleukin-6 (IL-6) is a multifunctional cytokine which plays an important role in a wide
range of biologic activities in different types of cell including tumor cells. IL-6 is involved in …

The IL-6 family of cytokines consists of IL-6, IL-11, IL-27, IL-31, oncostatin M (OSM),
leukaemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), cardiotrophin 1 (CT-1) …

The biology behind interleukin-6 targeted interventions : Current Opinion in Rheumatology The
biology behind interleukin-6 targeted interventions : Current Opinion in Rheumatology Log in or …