Skin ageing is a complex process that is determined by both intrinsic and extrinsic factors,
which leads to a progressive loss of structure and function. There is extensive evidence …

Skin aging is one of the most evident signs of human aging. Modification of the skin during
the life span is characterized by fine lines and wrinkling, loss of elasticity and volume, laxity …

Skin ageing is the result of a loss of cellular function, which can be further accelerated by
external factors. Mitochondria have important roles in skin function, and mitochondrial …

Here we aim to describe each factor that leads to skin aging and describe their mechanisms.
A PubMed database searches (from January 2004 to March 2014) using aging and skin as …

Skin aging is an inescapable phenomenon that leads to a functional decline of the skin
along with emergence of characteristics features such as coarse skin, wrinkles, loss of …

Oxidative stress is the resultant damage due to redox imbalances (increase in destructive
free radicals [reactive oxygen species (ROS)] and reduction in antioxidant …

Skin aging appears to be the result of two overlapping processes, intrinsic and extrinsic. It is
well accepted that oxidative stress contributes significantly to extrinsic skin aging, although …

Oxidative stress in skin plays a major role in the aging process. This is true for intrinsic aging
and even more for extrinsic aging. Although the results are quite different in dermis and …

Skin ageing is a complex process involving both internal and external factors, which leads to
a progressive loss of cutaneous function and structure. Solar radiation is the primary …

The skin is the main barrier that protects us against environmental stressors (physical,
chemical, and biological). These stressors, combined with internal factors, are responsible …