Activation of α2-adrenoreceptors suppresses the excitability of C1 spinal neurons having convergent inputs from tooth pulp and superior sagittal sinus in rats

M Takeda, T Tanimoto, M Takahashi, J Kadoi… - Experimental brain …, 2006 - Springer
The aim of the present study was to test the hypothesis that activation of α 2-adrenoreceptors
modulates the excitability of C1 neurons having convergent inputs from both the tooth pulp …

N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists suppress the superior sagittal sinus-evoked activity of C1 spinal neurons responding to tooth pulp …

Y Fujimi, M Takeda, T Tanimoto, S Matsumoto - Odontology, 2006 - Springer
The aim of the present study was to determine whether there is a convergence of inputs from
tooth pulp (TP) and the superior sagittal sinus (SSS) on rat C1 spinal neurons, and to …

Effects of N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists on excitation of the tooth-pulp-evoked C1 spinal neurons in the rat

M Takeda, T Tanimoto, S Matsumoto - Experimental brain research, 1999 - Springer
To examine whether there is a difference between the effects of iontophoretically applied N-
methyl-d-aspartate (NMDA) and non-NMDA receptor antagonists on the activity of C1 spinal …

Changes of the excitability of rat trigeminal root ganglion neurons evoked by α2-adrenoreceptors

M Takeda, M Ikeda, T Tanimoto, J Lipski, S Matsumoto - Neuroscience, 2002 - Elsevier
The aim of the study was to examine the effects of α2-adrenoreceptor agonists on the
excitability of trigeminal root ganglion (TRG) neurons using the perforated patch-clamp …

Suppressive effect of vagal afferents on cervical dorsal horn neurons responding to tooth pulp electrical stimulation in the rat

T Tanimoto, M Takeda, S Matsumoto - Experimental brain research, 2002 - Springer
The aim of the present study was to test the hypothesis that vagal afferent (VA) inputs modify
the tooth pulp (TP) stimulation-evoked activity of the first cervical dorsal horn (C1) neurons …

Inhibition of Glutamatergic Synaptic Input to Spinal Lamina IIo Neurons by Presynaptic α2-Adrenergic Receptors

YZ Pan, DP Li, HL Pan - Journal of neurophysiology, 2002 - journals.physiology.org
Activation of spinal α2-adrenergic receptors by the descending noradrenergic system and
α2-adrenergic agonists produces analgesia. However, the sites and mechanisms of the …

α2-Adrenoceptors Modulate NMDA-Evoked Responses of Neurons in Superficial and Deeper Dorsal Horn of the Medulla

KM Zhang, XM Wang, AM Peterson… - Journal of …, 1998 - journals.physiology.org
Kai-Ming Zhang, Xiao-Min Wang, Angela M. Peterson, Wen-Yan Chen, and Sukhbir S.
Mokha. α2-Adrenoceptors modulate NMDA-evoked responses of neurons in the superficial …

Effect of antisense knock-down of α2a-and α2c-adrenoceptors on the antinociceptive action of clonidine on trigeminal nociception in the rat

XM Wang, ZJ Zhang, R Bains, SS Mokha - Pain, 2002 - journals.lww.com
Although activation of α 2-adrenoceptors is known to play an important role in mediating
antinociception, the contribution of various α 2-adrenoceptor subtypes in modulating …

[引用][C] The role of 5-HT3 receptors in the vagal afferent activation-induced inhibition of C1 spinal neurons projected from tooth-pulp in the rat

T Tanimoto, M Takeda, T Nishikawa… - Journal of Pharmacology …, 2004 - ASPET
To test the hypothesis that vagal afferent (VA) stimulation modulates the first cervical dorsal
horn (C1) neuron activity, which is projected by tooth-pulp (TP) afferent inputs, through the …

Iontophoretic application of an A-type potassium channel blocker to the trigeminal ganglion neurons enhances the excitability of Aδ-and C-neurons innervating the …

N Hara, M Takeda, M Takahashi, S Matsumoto - Neuroscience research, 2012 - Elsevier
The present study tested the hypothesis that under in vivo conditions the iontophoretic
application of a IA channel blocker, 4-aminopyridine (4-AP), to the TRG neurons changes …