Solvent-free synthesis, in vitro and in silico studies of novel potential 1, 3, 4-thiadiazole-based molecules against microbial pathogens
IA Shehadi, MT Abdelrahman, M Abdelraof… - Molecules, 2022 - mdpi.com
A new series of 1, 3, 4-thiadiazoles was synthesized by the reaction of methyl 2-(4-hydroxy-3-
methoxybenzylidene) hydrazine-1-carbodithioate (2) with selected derivatives of …
methoxybenzylidene) hydrazine-1-carbodithioate (2) with selected derivatives of …
Utility of Bis‐Hydrazonoyl Chlorides as Precursors for Synthesis of New Functionalized Bis‐Thiadiazoles as Potent Antimicrobial Agents
SM Gomha, MS El_Gendy… - Journal of …, 2018 - Wiley Online Library
N′, N ″‐([1, 1'‐Biphenyl]‐4, 4′‐diyl) bis (2‐oxopropanehydrazonoyl chloride) is
considered to be the key intermediate for the synthesis of a variety bis‐1, 3, 4‐thiadiazole …
considered to be the key intermediate for the synthesis of a variety bis‐1, 3, 4‐thiadiazole …
Synthesis, antimicrobial evaluation and molecular docking of new functionalized bis (1, 3, 4-thiadiazole) and bis (thiazole) derivatives
Abstract Many bis-1, 3, 4-thiadiazoles 7, 10a, b, 13a-c and bis-thiazoles 16a-d, 19a-d were
synthesized from reaction of bis (hydrazonoyl) chloride 4 with a series of methyl …
synthesized from reaction of bis (hydrazonoyl) chloride 4 with a series of methyl …
Utility of 5-(furan-2-yl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide in the synthesis of heterocyclic compounds with antimicrobial activity
Background Pyrazolines show different biological activities. In recent years, interest in the
chemistry of hydrazonoyl halides has been renewed. 1, 3, 4-Thiadiazoles are one of the …
chemistry of hydrazonoyl halides has been renewed. 1, 3, 4-Thiadiazoles are one of the …
New 1, 3, 4‐thiadiazole derivatives: synthesis, characterization, and antimicrobial activity
AM Abo‐Bakr, HE Hashem - Journal of heterocyclic chemistry, 2019 - Wiley Online Library
In the present study, 2, 5‐bis (mercapto‐acetichydrazide)‐1, 3, 4‐thiadiazole (1) was utilized
by different reagents, namely, ethoxymethylene malononitrile, ethoxymethylene ethyl …
by different reagents, namely, ethoxymethylene malononitrile, ethoxymethylene ethyl …
Synthesis, characterization and molecular docking studies of highly functionalized and biologically active derivatives of 2-aminothiazole
G Kanagasabapathy, S Britto, V Anbazhagan - Journal of Molecular …, 2023 - Elsevier
Many derivatives of 2-aminothiazoles are found to have significant biological properties and
used as potential antibacterial and antifungal drugs. Therefore new synthetic methodologies …
used as potential antibacterial and antifungal drugs. Therefore new synthetic methodologies …
Synthesis and biological evaluation of new 1, 3, 4-thiadiazole derivatives as potent antimicrobial agents
Abstract A series of 1, 3, 4-thiadiazole derivatives were designed and synthesized using N-
(4-nitrophenyl) acetohydrazonoyl bromide and 1-[3, 5-dimethyl-1-(4-nitrophenyl)-1 H …
(4-nitrophenyl) acetohydrazonoyl bromide and 1-[3, 5-dimethyl-1-(4-nitrophenyl)-1 H …
Efficient synthesis, antibacterial, antifungal, antioxidant and cytotoxicity study of 2‐(2‐hydrazineyl) thiazole derivatives
VA Adole, RA More, BS Jagdale, TB Pawar… - …, 2020 - Wiley Online Library
In the present investigation, an alluring green PEG‐400 mediated one‐pot synthesis of
novel 2‐(2‐hydrazinyl) thiazole derivatives from 1, 2, 6, 7‐tetrahydro‐8H‐indeno [5, 4‐b] …
novel 2‐(2‐hydrazinyl) thiazole derivatives from 1, 2, 6, 7‐tetrahydro‐8H‐indeno [5, 4‐b] …
New and efficient approach for synthesis of novel bioactive [1, 3, 4] thiadiazoles incorporated with 1, 3-thiazole moiety
TA Farghaly, MA Abdallah, GS Masaret… - European Journal of …, 2015 - Elsevier
Abstract A series of novel 1, 3, 4-thiadiazoles incorporated with thiazole moiety was
synthesized by reaction of 5-acetyl-2-benzoylimino-3-phenyl-1, 3, 4-thiadiazole …
synthesized by reaction of 5-acetyl-2-benzoylimino-3-phenyl-1, 3, 4-thiadiazole …
Synthesis, characterization and anti-microbial activities of novel thiazole derivatives.
G Saravanan, V Alagarsamy, TGV Pavitra, GC Kumar… - 2010 - cabidigitallibrary.org
In the present study, a novel thiazoles were synthesized by incorporation of pyrazole moiety
at 2nd position of 2-hydrazinyl-N-(4-phenylthiazol-2-yl) acetamide (5) by treating with …
at 2nd position of 2-hydrazinyl-N-(4-phenylthiazol-2-yl) acetamide (5) by treating with …