Strategies, development, and pitfalls of therapeutic options for Alzheimer's disease
C Haas - Journal of Alzheimer's Disease, 2012 - content.iospress.com
Therapeutic options for Alzheimer's disease are currently limited to symptomatic treatment
that only provides modest and temporary maintenance of cognitive and memory functions …
that only provides modest and temporary maintenance of cognitive and memory functions …
Current perspectives on pharmacotherapy of Alzheimer's disease
K Chopra, S Misra, A Kuhad - Expert opinion on pharmacotherapy, 2011 - Taylor & Francis
Introduction: Alzheimer's disease (AD) is a daunting public health threat that has prompted
the scientific community's ongoing efforts to decipher the underlying disease mechanism …
the scientific community's ongoing efforts to decipher the underlying disease mechanism …
Emerging therapeutics for Alzheimer's disease
K Chiang, EH Koo - Annual review of pharmacology and …, 2014 - annualreviews.org
Despite decades of intense research, therapeutics for Alzheimer's disease (AD) are still
limited to symptomatic treatments that possess only short-term efficacy. Recently, several …
limited to symptomatic treatments that possess only short-term efficacy. Recently, several …
Overcoming translational barriers impeding development of Alzheimer's disease modifying therapies
TE Golde - Journal of neurochemistry, 2016 - Wiley Online Library
It has now been~ 30 years since the Alzheimer's disease (AD) research entered what may
be termed the 'molecular era'that began with the identification of the amyloid β protein (Aβ) …
be termed the 'molecular era'that began with the identification of the amyloid β protein (Aβ) …
Advances in the therapy of Alzheimer's disease: targeting amyloid beta and tau and perspectives for the future
H Hampel, LS Schneider, E Giacobini… - Expert review of …, 2015 - Taylor & Francis
Worldwide multidisciplinary translational research has led to a growing knowledge of the
genetics and molecular pathogenesis of Alzheimer's disease (AD) indicating that …
genetics and molecular pathogenesis of Alzheimer's disease (AD) indicating that …
Current advances in the treatment of Alzheimer's disease: focused on considerations targeting Aβ and tau
Y Hong-Qi, S Zhi-Kun, C Sheng-Di - Translational neurodegeneration, 2012 - Springer
Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mainly the memory
and cognitive function in elderly. Extracellular beta amyloid deposition and intracellular tau …
and cognitive function in elderly. Extracellular beta amyloid deposition and intracellular tau …
Current druggable targets for therapeutic control of Alzheimer's disease
GL Gupta, NP Samant - Contemporary Clinical Trials, 2021 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative brain disorder that has an increasingly
large burden on health and social care systems. The pathophysiology involves the …
large burden on health and social care systems. The pathophysiology involves the …
Treatment of Alzheimer's disease: current management and experimental therapeutics
LS Honig, CD Boyd - Current translational geriatrics and experimental …, 2013 - Springer
Alzheimer's disease (AD) is a major cause of morbidity in the elderly. AD affects over 5
million persons in the United States, but because it increases in incidence in the elderly, and …
million persons in the United States, but because it increases in incidence in the elderly, and …
An effective treatment for Alzheimer's disease must consider both amyloid and tau
CJ Lansdall - Bioscience Horizons, 2014 - academic.oup.com
Alzheimer's disease (AD) is a devastating neurodegenerative disorder resulting in cognitive
impairment, loss of executive functions and progressive dementia. AD is the most common …
impairment, loss of executive functions and progressive dementia. AD is the most common …
Alzheimer's disease: strategies for disease modification
M Citron - Nature reviews Drug discovery, 2010 - nature.com
Alzheimer's disease is the largest unmet medical need in neurology. Current drugs improve
symptoms, but do not have profound disease-modifying effects. However, in recent years …
symptoms, but do not have profound disease-modifying effects. However, in recent years …
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