Phagocytosis of Cryptococcus neoformans by, and Nonlytic Exocytosis from, Acanthamoeba castellanii

CJ Chrisman, M Alvarez… - Applied and …, 2010 - Am Soc Microbiol
Cryptococcus neoformans, an encapsulated, pathogenic yeast, is endowed with a variety of
virulence factors, including a polysaccharide capsule. During mammalian infection, the …

Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide …

SC Tucker, A Casadevall - Proceedings of the National …, 2002 - National Acad Sciences
Cryptococcus neoformans (CN), an encapsulated, ubiquitous environmental yeast, is
pathogenic for humans, primarily those with compromised immune function. CN is believed …

Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages

JN Steenbergen, HA Shuman… - Proceedings of the …, 2001 - National Acad Sciences
Cryptococcus neoformans (Cn) is a soil fungus that causes life-threatening meningitis in
immunocompromised patients and is a facultative intracellular pathogen capable of …

Analysis of multiple components involved in the interaction between Cryptococcus neoformans and Acanthamoeba castellanii

J Rizzo, PC Albuquerque, JM Wolf, R Nascimento… - Fungal biology, 2017 - Elsevier
Cryptococcus neoformans is an environmental fungus that can cause lethal
meningoencephalitis in immunocompromised individuals. The mechanisms by which …

Nonlytic Exocytosis of Cryptococcus neoformans from Macrophages Occurs In Vivo and Is Influenced by Phagosomal pH

AM Nicola, EJ Robertson, P Albuquerque… - MBio, 2011 - Am Soc Microbiol
ABSTRACT A unique aspect of the interaction of the fungus Cryptococcus neoformans with
macrophages is the phenomenon of nonlytic exocytosis, also referred to as “vomocytosis” or …

[HTML][HTML] Phagosome extrusion and host-cell survival after Cryptococcus neoformans phagocytosis by macrophages

M Alvarez, A Casadevall - Current Biology, 2006 - cell.com
Cryptococcus neoformans (Cn) is an encapsulated yeast that is a facultative intracellular
pathogen and a frequent cause of human disease. The interaction of Cn with alveolar …

The transcriptional response of Cryptococcus neoformans to ingestion by Acanthamoeba castellanii and macrophages provides insights into the evolutionary …

LS Derengowski, HC Paes, P Albuquerque… - Eukaryotic …, 2013 - Am Soc Microbiol
Virulence of Cryptococcus neoformans for mammals, and in particular its intracellular style,
was proposed to emerge from evolutionary pressures on its natural environment by …

Extracellular Vesicles from Cryptococcus neoformans Modulate Macrophage Functions

DL Oliveira, CG Freire-de-Lima… - Infection and …, 2010 - Am Soc Microbiol
Cryptococcus neoformans and distantly related fungal species release extracellular vesicles
that traverse the cell wall and contain a varied assortment of components, some of which …

Does amoeboid reasoning explain the evolution and maintenance of virulence factors in Cryptococcus neoformans?

SM Levitz - Proceedings of the National Academy of …, 2001 - National Acad Sciences
Cryptococcus neoformans is a model or-ganism for the study of fungal infections. This
encapsulated fungus is found worldwide, particularly in soil samples contaminated by bird …

Dissociation of a hydrophobic surface from phagocytosis of encapsulated and non-encapsulated Cryptococcus neoformans

TR Kozel - Infection and immunity, 1983 - Am Soc Microbiol
Cryptococcus neoformans is surrounded by a capsular polysaccharide that inhibits
phagocytosis of the yeast by macrophages. This capsular polysaccharide also confers …