[HTML][HTML] Cannabidiol affects extracellular vesicle release, miR21 and miR126, and reduces prohibitin protein in glioblastoma multiforme cells
US Kosgodage, P Uysal-Onganer, A MacLatchy… - Translational …, 2019 - Elsevier
Glioblastoma multiforme (GBM) is the most common and aggressive form of primary
malignant brain tumor in adults, with poor prognosis. Extracellular vesicles (EVs) are key …
malignant brain tumor in adults, with poor prognosis. Extracellular vesicles (EVs) are key …
[HTML][HTML] Cannabidiol induces cell cycle arrest and cell apoptosis in human gastric cancer SGC-7901 cells
X Zhang, Y Qin, Z Pan, M Li, X Liu, X Chen, G Qu… - Biomolecules, 2019 - mdpi.com
The main chemical component of cannabis, cannabidiol (CBD), has been shown to have
antitumor properties. The present study examined the in vitro effects of CBD on human …
antitumor properties. The present study examined the in vitro effects of CBD on human …
[HTML][HTML] Anti-proliferative and cytotoxic effect of cannabidiol on human cancer cell lines in presence of serum
A Sainz-Cort, C Müller-Sánchez, E Espel - BMC research notes, 2020 - Springer
Objective Cannabinoids are able to reduce tumor growth in xenograft models, but their
therapeutic potential as anti-cancer drugs in humans is unclear yet. In vitro studies of the …
therapeutic potential as anti-cancer drugs in humans is unclear yet. In vitro studies of the …
Cannabinoid signaling in glioma cells
A Ellert-Miklaszewska, IA Ciechomska, B Kaminska - Glioma Signaling, 2020 - Springer
Cannabinoids are a group of structurally heterogeneous but pharmacologically related
compounds, including plant-derived cannabinoids, synthetic substances and endogenous …
compounds, including plant-derived cannabinoids, synthetic substances and endogenous …
Δ9-Tetrahydrocannabinol inhibits cell cycle progression by downregulation of E2F1 in human glioblastoma multiforme cells
G Galanti, T Fisher, I Kventsel, J Shoham… - Acta …, 2008 - Taylor & Francis
Background. The active components of Cannabis sativa L., Cannabinoids, traditionally used
in the field of cancer for alleviation of pain, nausea, wasting and improvement of well-being …
in the field of cancer for alleviation of pain, nausea, wasting and improvement of well-being …
[HTML][HTML] Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis
ÁC Murphy, B Weyhenmeyer, J Noonan, SM Kilbride… - Apoptosis, 2014 - Springer
Glioblastoma (GBM) is the most aggressive form of primary brain tumour, with dismal patient
outcome. Treatment failure is associated with intrinsic or acquired apoptosis resistance and …
outcome. Treatment failure is associated with intrinsic or acquired apoptosis resistance and …
[HTML][HTML] A low dose of pure cannabidiol is sufficient to stimulate the cytotoxic function of cik cells without exerting the downstream mediators in pancreatic cancer cells
F Garofano, A Sharma, H Abken… - International Journal of …, 2022 - mdpi.com
Despite numerous studies conducted over the past decade, the exact role of the
cannabinoid system in cancer development remains unclear. Though research has focused …
cannabinoid system in cancer development remains unclear. Though research has focused …
[HTML][HTML] Cannabidiol inhibits tumorigenesis in cisplatin-resistant non-small cell lung cancer via TRPV2
Simple Summary Drug resistance is the key factor contributing to the therapeutic failure of
lung cancer and the deaths related to lung cancer. Our study demonstrated that small …
lung cancer and the deaths related to lung cancer. Our study demonstrated that small …
Hypothesis: cannabinoid therapy for the treatment of gliomas?
Gliomas, in particular glioblastoma multiforme or grade IV astrocytoma, are the most
frequent class of malignant primary brain tumours and one of the most aggressive forms of …
frequent class of malignant primary brain tumours and one of the most aggressive forms of …
Effects on cell viability
M Guzman - Cannabinoids, 2005 - Springer
Cannabinoids are known to control the cell survival/death decision, leading to different
outcomes that depend on the nature of the target cell and its proliferative or differentiation …
outcomes that depend on the nature of the target cell and its proliferative or differentiation …