MgCHA particles dispersion in porous PCL scaffolds: in vitro mineralization and in vivo bone formation

V Guarino, S Scaglione, M Sandri… - Journal of tissue …, 2014 - Wiley Online Library
In this work, we focus on the in vitro and in vivo response of composite scaffolds obtained by
incorporating Mg, CO3‐doped hydroxyapatite (HA) particles in poly (ε‐caprolactone)(PCL) …

Injectable PLGA microspheres with tunable magnesium ion release for promoting bone regeneration

Z Yuan, P Wei, Y Huang, W Zhang, F Chen, X Zhang… - Acta biomaterialia, 2019 - Elsevier
Abstract Magnesium ions (Mg 2+) are bioactive and proven to promote bone tissue
regeneration, in which the enhancement efficiency is closely related to Mg 2+ …

Fabrication techniques involved in developing the composite scaffolds PCL/HA nanoparticles for bone tissue engineering applications

S Murugan, SR Parcha - Journal of Materials Science: Materials in …, 2021 - Springer
A fine-tuned combination of scaffolds, biomolecules, and mesenchymal stem cells (MSCs) is
used in tissue engineering to restore the function of injured bone tissue and overcome the …

Independent effects of the chemical and microstructural surface properties of polymer/ceramic composites on proliferation and osteogenic differentiation of human …

L Sun, CB Danoux, Q Wang, D Pereira, D Barata… - Acta biomaterialia, 2016 - Elsevier
Within the general aim of finding affordable and sustainable regenerative solutions for
damaged and diseased tissues and organs, significant efforts have been invested in …

Dispersion of hydroxyapatite nanoparticles in solution and in polycaprolactone composite scaffolds

CS Goonasekera, KS Jack, JJ Cooper-White… - Journal of Materials …, 2016 - pubs.rsc.org
The dispersion behaviour of hydroxyapatite nanoparticles (HAP) and surface-modified HAP
was studied in 1, 4-dioxane (DO), water and poly (ε-caprolactone)(PCL) solutions and the …

Surface modification of biodegradable Mg-based scaffolds for human mesenchymal stem cell proliferation and osteogenic differentiation

SH Wang, SP Lee, CW Yang, CM Lo - Materials, 2021 - mdpi.com
Magnesium alloys with coatings have the potential to be used for bone substitute
alternatives since their mechanical properties are close to those of human bone. However …

Characterization of biomimetic silicate-and strontium-containing hydroxyapatite microparticles embedded in biodegradable electrospun polycaprolactone scaffolds for …

RA Surmenev, S Shkarina, DS Syromotina… - European Polymer …, 2019 - Elsevier
A significant need exists today to develop novel alternatives to traditional bone grafts. Here,
we report the potential use of mechanochemically synthesized hydroxyapatite (HA), silicate …

In vivo lamellar bone formation in fibre coated MgCHA–PCL-composite scaffolds

S Scaglione, V Guarino, M Sandri, A Tampieri… - Journal of Materials …, 2012 - Springer
Bio-inspired materials with controlled topography have gained increasing interest in
regenerative medicine, because of their ability to reproduce the physical features of natural …

Comparative study of PCL-HAp and PCL-bioglass composite scaffolds for bone tissue engineering

J Rodenas-Rochina, JLG Ribelles… - Journal of Materials …, 2013 - Springer
The aim of this work is to compare the effect of hydroxyapatite (HAp) or bioglass (BG)
nanoparticles in a polycaprolactone composite scaffold aimed to bone regeneration. To …

Hybrid structure in PCL-HAp scaffold resulting from biomimetic apatite growth

M Lebourg, JS Anton, JLG Ribelles - Journal of materials science …, 2010 - Springer
Polymer–ceramic composites are favourite candidates when aiming to replace bone tissue.
We present here scaffolds made of polycaprolactone-hydroxyapatite (PCL-HAp) composites …