[HTML][HTML] Genkwanin: An emerging natural compound with multifaceted pharmacological effects

N El Menyiy, S Aboulaghras, S Bakrim… - Biomedicine & …, 2023 - Elsevier
Plant bioactive molecules could play key preventive and therapeutic roles in chronological
aging and the pathogenesis of many chronic diseases, often accompanied by increased …

[HTML][HTML] Berberine is a potential therapeutic agent for metabolic syndrome via brown adipose tissue activation and metabolism regulation

X Hu, Y Zhang, Y Xue, Z Zhang… - American journal of …, 2018 - ncbi.nlm.nih.gov
Berberine (BBR), an isoquinoline alkaloid that derived from the Chinese medicinal plant
Coptis chinensis, has been identified with multiple pharmacological activities, including …

Alisol B blocks the development of HFD-induced obesity by triggering the LKB1-AMPK signaling in subcutaneous adipose tissue

L Yang, L Li, Q Lu, L Li, C Xie, F Jiang, H Li… - European journal of …, 2023 - Elsevier
As a global epidemic disease, obesity causes dysfunction of glucose and lipid metabolism
leading to persistently high morbidity and mortality. Given the difficulty to achieve and …

Pharmacological activities and therapeutic potential of kaempferitrin in medicine for the treatment of human disorders: A review of medicinal importance and health …

DK Patel - … & Haematological Disorders-Drug Targets (Formerly …, 2021 - ingentaconnect.com
Background: Herbal drugs and their derived phytochemicals are valuable for human beings
as a source of a vital component of food material and drugs. Flavonoids are naturally …

Urolithin A, a gut metabolite, improves insulin sensitivity through augmentation of mitochondrial function and biogenesis

AM Toney, R Fan, Y Xian, V Chaidez, AE Ramer‐Tait… - …, 2019 - Wiley Online Library
Objective Urolithin A (UroA) is a major metabolite of ellagic acid produced following
microbial catabolism in the gut. Emerging evidence has suggested that UroA modulates …

Distinct AMPK-mediated FAS/HSL pathway is implicated in the alleviating effect of nuciferine on obesity and hepatic steatosis in HFD-fed mice

H Xu, X Lyu, X Guo, H Yang, L Duan, H Zhu, H Pan… - Nutrients, 2022 - mdpi.com
Nuciferine (Nuci), the main aporphine alkaloid component in lotus leaf, was reported to
reduce lipid accumulation in vitro. Herein we investigated whether Nuci prevents obesity in …

[HTML][HTML] Farnesoid X receptor regulators from natural products and their biological function

P Wan, NI Hengfan, GUO Dale, D Yun… - Journal of Traditional …, 2023 - ncbi.nlm.nih.gov
Metabolic syndrome (MetS) has been a growing public health concern worldwide without
specific medicine. Through summarizing the chemical structure type and effect mechanisms …

[HTML][HTML] Prospective multifunctional roles and pharmacological potential of dietary flavonoid narirutin

S Mitra, MS Lami, TM Uddin, R Das, F Islam… - Biomedicine & …, 2022 - Elsevier
Plant-based phytochemicals are now being used to treat plenty of physiological diseases.
Herbal drugs have gained popularity in recent years because of their strength, purity, and …

Amorfrutin B is an efficient natural peroxisome proliferator-activated receptor gamma (PPARγ) agonist with potent glucose-lowering properties

C Weidner, SJ Wowro, A Freiwald, K Kawamoto… - Diabetologia, 2013 - Springer
Aims/hypothesis The nuclear receptor peroxisome proliferator-activated receptor gamma
(PPARγ) is an important gene regulator in glucose and lipid metabolism. Unfortunately …

Rhodiola and salidroside in the treatment of metabolic disorders

XL Bai, XL Deng, GJ Wu, WJ Li… - Mini Reviews in Medicinal …, 2019 - ingentaconnect.com
Over the past three decades, the knowledge gained about the mechanisms that underpin
the potential use of Rhodiola in stress-and ageing-associated disorders has increased, and …