Lead anti-obesity compounds from nature

V Dahiya, N Vasudeva, S Sharma… - … Metabolic & Immune …, 2020 - ingentaconnect.com
Background: Obesity has become a global issue, leading to increased risk of metabolic
syndrome, which encompasses diabetes, cardiovascular disease, stroke, hypertension, and …

Development of an HPLC fluorescence method for determination of boldine in plasma, bile and urine of rats and identification of its major metabolites by LC–MS/MS

M Hroch, S Mičuda, J Cermanová, J Chládek… - … of Chromatography B, 2013 - Elsevier
Boldine belongs to the group of aporphine alkaloids isolated from Boldo tree. In contrast with
numerous reports on the pharmacological effects of boldine, the data about its …

Pentacyclic triterpenes: New tools to fight metabolic syndrome

H Sharma, P Kumar, RR Deshmukh, A Bishayee… - Phytomedicine, 2018 - Elsevier
Background: Metabolic syndrome is a combination of dysregulated cardiometabolic risk
factors characterized by dyslipidemia, impaired glucose tolerance, insulin resistance …

Salidroside-can it be a multifunctional drug?

SKJ Magani, SD Mupparthi, BP Gollapalli… - Current Drug …, 2020 - ingentaconnect.com
Background: Salidroside is a glucoside of tyrosol found mostly in the roots of Rhodiola spp. It
exhibits diverse biological and pharmacological properties. In the last decade, enormous …

Parthenolide inhibits lipid accumulation via activation of Nrf2/Keap1 signaling during adipocyte differentiation

CY Kim, B Kang, J Hong, HS Choi - Food Science and Biotechnology, 2020 - Springer
The effects of parthenolide (PL), a sesquiterpene lactone obtained from feverfew plant, on
lipid accumulation and signaling pathway in adipocytes were investigated. PL significantly …

[HTML][HTML] Emodin palliates high-fat diet-induced nonalcoholic fatty liver disease in mice via activating the farnesoid X receptor pathway

C Shen, Z Pan, S Wu, M Zheng, C Zhong, X Xin… - Journal of …, 2021 - Elsevier
Abstract Background Cassia mimosoides Linn (CMD) is a traditional Chinese herb that
clears liver heat and dampness. It has been widely administered in clinical practice to treat …

1H nuclear magnetic resonance based-metabolomic characterization of Peucedani Radix and simultaneous determination of praeruptorin A and praeruptorin B

YL Song, WH Jing, YG Chen, YF Yuan, R Yan… - … of Pharmaceutical and …, 2014 - Elsevier
As a widely used traditional herbal medicine, it is crucial to characterize the holistic
metabolic profile of Peucedani Radix (Chinese name: Qian-hu). However, it is quite arduous …

Targeting metabolic disorders by natural products

O Tabatabaei-Malazy, B Larijani… - Journal of Diabetes & …, 2015 - Springer
The most prevalent metabolic disorders are diabetes mellitus, obesity, dyslipidemia,
osteoporosis and metabolic syndrome, which are developed when normal metabolic …

[PDF][PDF] Update on the benefits and mechanisms of action of the bioactive vegetal alkaloid berberine on lipid metabolism and homeostasis

Y Wang, JA Zidichouski - Cholesterol, 2018 - downloads.hindawi.com
1. Background Berberine (BBR) is a quaternary ammonium salt derived from the
protoberberine group of benzylisoquinoline alkaloids (Figure 1). It is the principal bioactive …

Review on the diverse biological effects of glabridin

J Zhang, X Wu, B Zhong, Q Liao, X Wang… - Drug Design …, 2023 - Taylor & Francis
Glabridin is a prenylated isoflavan from the roots of Glycyrrhiza glabra Linne and has posed
great impact on the areas of drug development and medicine, due to various biological …