The number of cases of obesity and type 2 diabetes mellitus (T2DM) is part of the metabolic
syndrome case. Purslane (Portulaca oleracea L.) is a plant that has been clinically tested …

Insulin resistance has a critical role in type 2 diabetes. The aim of this study was to
investigate the effect of pinobanksin, galangin, chrysin, and pinocembrin from propolis on …

In screening a library of plant extracts from~ 1000 species native to the Southeastern United
States, Lobelia cardinalis was identified as containing nicotinic acetylcholine receptor …

Objective Urolithin A (UroA) is a major metabolite of ellagic acid produced following
microbial catabolism in the gut. Emerging evidence has suggested that UroA modulates …

Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder with
limited therapeutic agents. Rhynchophylline (RIN), a tetracyclic oxindole alkaloid isolated …

Urolithins (eg, UroA and B) are gut microbiota-derived metabolites of the natural polyphenol
ellagic acid. Urolithins are associated with various health benefits, including attenuation of …

Brown adipose tissue (BAT) and beige adipose tissue dissipate metabolic energy and
mediate nonshivering thermogenesis, thereby boosting energy expenditure. Increasing the …

Nine alkaloids with three different structural skeletons were isolated from Dicranostigma
leptopodum (Maxim.) Fedde (Papaveraceae) by repeated silica gel column …

Context: Prenylated flavonoids are a unique class of naturally occurring flavonoids that exist
especially for the plant's self-defensive strategy. This special class of flavonoids increases …

It was previously reported that prenylated flavonols from Sophora flavescens are inhibitors of
rat lens aldose reductase (RLAR), human recombinant aldose reductase (HRAR), advanced …