Background Autoimmune mechanisms have been implicated in the pathogenesis of chronic
ongoing myocarditis. To investigate this relation, we used an A/J mouse model inoculated …

We investigated the suppressive effects of immunoglobulin (Ig) on effector T cells in
autoimmune myocarditis. Treatment with Ig reduced production of the so-called T-helper …

Background The hypothesis that viral myocarditis causes an autoimmune response and
subsequent dilated cardiomyopathy is controversial. To further investigate the autoimmune …

Excellent animal models are available for virus-induced and autoimmune heart disease that
are remarkably similar to human disease. Developing good animal models for heart disease …

LB Stull, NA DiIulio, M. Yu, CF McTiernan, NB Ratliff, VK Tuohy and C. Schomisch Moravec.
Alterations in Cardiac Function and Gene Expression during Autoimmune Myocarditis in …

Autoimmne mechanisms have been implicated in the pathogenesis of chronic ongoing
mycarditis. An earlier study of murine chronic ongoing myocarditis reported that infiltrating T …

One possible mechanism for neurohumoral activation after myocardial infarction may be the
generation of an immune response against cardiac self-antigens. We hypothesize that if …

Cardiotropic virus infection of mice typically produces florid myocardial inflammation and, in
certain strains, elicits a chronic postinfectious autoimmune myocarditis. In humans …

Following infection with Coxsackievirus B3 (CVB3). A‐strain mice develop ongoing
myocarditis that persists after the virus ceases to be cultivatable from heart tissue. We …

Cardiovascular diseases are the leading cause of death in industrialized nations worldwide.
Of all deaths resulting from cardiovascular diseases, 2% are caused by inflammatory heart …