18F-Fluorodeoxyglucose Positron Emission Tomographic Imaging of Pulmonary Functions, Pathology, and Drug Delivery

MB Dolovich - Proceedings of the American Thoracic Society, 2009 - atsjournals.org
18F-FDG positron emission tomographic (PET) scanning is a major imaging tool widely
used to investigate lung function and lung disease. Tomographic imaging of drug delivered …

Imaging drug delivery and drug responses in the lung

M Dolovich, R Labiris - Proceedings of the American Thoracic …, 2004 - atsjournals.org
Conventional two-dimensional and three-dimensional single photon emission computed
tomography and positron emission tomography imaging tools and specific inhaled …

Lung physiology and aerosol deposition imaged with positron emission tomography

J Venegas, T Winkler, RS Harris - Journal of aerosol medicine and …, 2013 - liebertpub.com
Physiological conditions and pathophysiological changes in the lungs may affect many
applications in aerosol medicine and pulmonary drug delivery. In the diseased lung, spatial …

Positron emission tomography (PET) for assessing aerosol deposition of orally inhaled drug products

MB Dolovich, DL Bailey - … of aerosol medicine and pulmonary drug …, 2012 - liebertpub.com
The topical distribution of inhaled therapies in the lung can be viewed using radionuclides
and imaging. Positron emission tomography (PET) is a three-dimensional functional imaging …

Measuring total and regional lung deposition using inhaled radiotracers

MB Dolovich - Journal of Aerosol Medicine, 2001 - liebertpub.com
The delivery of an inhaled drug to the lungs can be measured by adding a γ-emitting
radiotracer to the formulation and using two-dimensional planar imaging or three …

PET imaging-based evaluation of aerosol drugs and their delivery devices: nasal and pulmonary studies

Z Lee, MS Berridge - IEEE transactions on medical imaging, 2002 - ieeexplore.ieee.org
Three-dimensional (3-D) positron emission tomography (PET) imaging of inhaled
radiolabeled aerosol in the nasal or pulmonary regions provides an in vivo measurement of …

Lung imaging—two dimensional gamma scintigraphy, SPECT, CT and PET

J Conway - Advanced drug delivery reviews, 2012 - Elsevier
This review will cover the principles of imaging the deposition of inhaled drugs and some of
the state-of-the art imaging techniques being used today. Aerosol deposition can be imaged …

Radionuclide scanning, respiratory physiology, and pharmacokinetics

GC Smaldone - Journal of Aerosol Medicine, 2001 - liebertpub.com
THE CURRENT ISSUE OF THE Journal of Aerosol Medicine contains articles devoted to
gamma camera imaging. The gamma camera has proved invaluable in the advancement of …

Imaging pulmonary inflammation with positron emission tomography: a biomarker for drug development

DL Chen, DP Schuster - Molecular pharmaceutics, 2006 - ACS Publications
Methods currently used to assess lung and airway inflammation are often poorly
quantitative, invasive, nonspecific, or insensitive. Positron emission tomography (PET) with …

Imaging in aerosol medicine

TE Corcoran - Respiratory Care, 2015 - rc.rcjournal.com
Imaging techniques have been used extensively to study the delivery of inhaled
medications. Deposition scintigraphy involves the quantification of deposited aerosol dose …