Galanin transgenic mice display cognitive and neurochemical deficits characteristic of Alzheimer's disease
RA Steiner, JG Hohmann, A Holmes… - Proceedings of the …, 2001 - National Acad Sciences
Galanin is a neuropeptide with multiple inhibitory actions on neurotransmission and
memory. In Alzheimer's disease (AD), increased galanin-containing fibers hyperinnervate …
memory. In Alzheimer's disease (AD), increased galanin-containing fibers hyperinnervate …
Galanin–25 years with a multitalented neuropeptide: Galanin impairs cognitive abilities in rodents: relevance to Alzheimer's Disease
JN Crawley - Cellular and Molecular Life Sciences, 2008 - Springer
The neuropeptide galanin and its receptors are localized in brain pathways mediating
learning and memory. Central microinjection of galanin impairs performance of a variety of …
learning and memory. Central microinjection of galanin impairs performance of a variety of …
Galanin inhibits performance on rodent memory tasks
MP McDONALD, TC Gleason… - Annals of the New …, 1998 - Wiley Online Library
Central administration of galanin produces performance deficits on a variety of rodent
learning and memory tasks. Galanin impairs acquisition and/or retention of the Morris water …
learning and memory tasks. Galanin impairs acquisition and/or retention of the Morris water …
[HTML][HTML] Galanin-acetylcholine interactions in rodent memory tasks and Alzheimer's disease.
MP McDonald, JN Crawley - Journal of Psychiatry and …, 1997 - ncbi.nlm.nih.gov
Galanin is a 29-amino-acid neuropeptide that is widely distributed in the mammalian central
nervous system. Galanin-immunoreactive cell bodies, fibres and terminals, and galanin …
nervous system. Galanin-immunoreactive cell bodies, fibres and terminals, and galanin …
Galanin: neurobiologic mechanisms and therapeutic potential for Alzheimer's disease
SE Counts, SE Perez, U Kahl, T Bartfai… - CNS Drug …, 2001 - Wiley Online Library
The neuropeptide galanin (GAL) is widely distributed in the mammalian CNS. Several lines
of evidence suggest that GAL may play a critical role in cognitive processes such as memory …
of evidence suggest that GAL may play a critical role in cognitive processes such as memory …
Galanin impairs performance on learning and memory tasks: findings from galanin transgenic and GAL-R1 knockout mice
Galanin (GAL) impairs performance on cognitive tasks when administered centrally to rats.
GAL transgenic (GAL-tg) mice overexpressing endogenous GAL show deficits on the probe …
GAL transgenic (GAL-tg) mice overexpressing endogenous GAL show deficits on the probe …
Galanin Expression within the Basal Forebrain in Alzheimer's Disease: Comments on Therapeutic Potentiala
The inhibitory neuropeptide galanin has widespread distribution throughout the central
nervous system. Studies indicate that galanin modulates cognition by regulating cholinergic …
nervous system. Studies indicate that galanin modulates cognition by regulating cholinergic …
Galanin–25 years with a multitalented neuropeptide: Galanin in Alzheimer's disease: Neuroinhibitory or neuroprotective?
SE Counts, SE Perez, EJ Mufson - Cellular and Molecular Life Sciences, 2008 - Springer
Galanin (GAL) and GAL receptors (GALRs) are overexpressed in degenerating brain
regions associated with cognitive decline in Alzheimer's disease (AD). The functional …
regions associated with cognitive decline in Alzheimer's disease (AD). The functional …
Functional interactions of galanin and acetylcholine: relevance to memory and Alzheimer's disease
JN Crawley - Behavioural brain research, 1993 - Elsevier
Galanin, a 29-amino acid neuropeptide, is the only peptide known to coexist with
acetylcholine in the basal forebrain neurons which degenerate early in the progression of …
acetylcholine in the basal forebrain neurons which degenerate early in the progression of …
Galanin-acetylcholine interactions: relevance to memory and Alzheimer's disease
JN Crawley - Life sciences, 1996 - Elsevier
The neuropeptide, galanin, and its receptors are localized in the cholinergic basal forebrain
and its projection areas in mammalian brain. Centrally administered galanin inhibits …
and its projection areas in mammalian brain. Centrally administered galanin inhibits …
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