A rapid and sensitive high-performance liquid chromatography (HPLC) method was
developed and validated in rat plasma and tissue (heart, liver, kidney and lung) …

A liquid chromatographic‐mass spectrometry (LC/MS) assay method was developed for the
determination of amiodarone and desethylamiodarone in rat specimens. Analytes were …

A simple and sensitive high-performance liquid chromatographic method for the
simultaneous assay of amiodarone and desethylarniodarone in plasma, urine and tissues …

A rapid method for the quantification of amiodarone and desethylamiodarone in animal
plasma using high-performance liquid chromatography combined with UV detection (HPLC …

A stable isotope dilution liquid chromatography–electrospray ionization tandem mass
spectrometry (LC–MS/MS) assay to measure amiodarone, the most frequently used agent …

A sensitive and specific high-performance liquid chromatography–electrospray ionization-
tandem mass spectrometry (HPLC–ESI-MS–MS) method has been developed for the …

A novel method was developed for the determination of amiodarone and
desethylamiodarone by high-performance liquid chromatography (HPLC) coupled with …

Purpose. A high-performance liquid chromatographic method is described for the
determination of amiodarone in rat plasma. Methods. After liquid-liquid extraction, the …

Amiodarone, an antiarrhythmic benzofuran derivative has been widely used outside of the
United States for as long as ten years [I]. In the USA it remains an investigational drug which …

In mammals, mono-N-desethylamiodarone (MDEA) is the only known metabolite of
amiodarone. Our previous experiments demonstrated that in vitro MDEA may be …