Current evidence suggests heredity and metabolic syndrome contributes to gout
progression. Specifically, the WDR1 and CLNK genes may play a role in gout progression in …

Gout is a common inflammatory arthritis triggered by the presence of monosodium urate
(MSU) crystals in joints and connective tissues. Current evidence suggests that heredity …

A genome-wide association study of gout in European populations identified 12 genetic
variants strongly associated with risk of gout, but it is unknown whether these variants are …

Gout is the most common form of inflammatory arthritis affecting men, and current evidence
suggests that genetic factors contribute to its progression. As a previous study identified that …

Previous studies have shown that the PDK2 and ABCG2 genes play important roles in many
aspects of gout development in European populations. However, a detailed genotype …

Objective The Māori and Pacific (Polynesian) population of Aotearoa New Zealand has a
high prevalence of gout. Our aim was to identify potentially functional missense genetic …

Background Gout is a common arthritic disease resulting from elevated serum uric acid
(SUA) level. A large meta-analysis including 28,141 individuals identified nine single …

Chromosome 4q25 has been identified as a genomic region associated with gout. However,
the associations of gout with the genes in this region have not yet been confirmed. Here, we …

Gout is a common arthritis resulting from increased serum urate, and many loci have been
identified that are associated with serum urate and gout. However, their influence on the …

Background and objective: Gout is a common form of inflammatory arthritis caused by the
crystallization of uric acid. Previous studies have demonstrated that the genetic …