Objective To study the associations of gout, tophi and uric acid levels with the gout-related
SLC2A9 (solute carrier family 2, member 9) single nucleotide polymorphisms (SNPs) …

Gout is a common form of inflammatory arthritis caused by crystallization of acid uric in the
joints. The development of gout is not only triggered by environmental factors but also by …

OBJECTIVE To assess the association of single nucleotide polymorphisms (SNPs) of
susceptibility genes of type 2 diabetes mellitus (T2DM) with liability to gout among ethnic …

The aim of the present study was to investigate the association between seven functional
SNPs in NALP3 gene and the susceptibility to primary gout. A total of 247 patients with …

Polymorphisms have been identified to predispose to primary gouty arthritis (GA) and
hyperuricemia (HUA). Here, we accessed the five polymorphisms of rs10754558 …

Objectives To identify genetic variants and polygenic risk score (PRS) relating to female gout
and asymptomatic hyperuricaemia (AH) in a genome-wide association study (GWAS) …

Gout is a chronic disease resulting from elevated serum urate (SU). Previous genome-wide
association studies (GWAS) have identified dozens of susceptibility loci for SU/gout, but few …

The pathogenesis of gout involves a series of steps beginning with hyperuricaemia, followed
by the deposition of monosodium urate crystal in articular structures and culminating in an …

Despite progress in understanding of the genetic basis of gout, the precise factors affecting
differences in gout susceptibility among different gout subtypes remain unclear. Using …

Gout is the most frequent inXammatory joint disease in men above 40 years of age (Luk and
Simkin 2005). Recently, a genome-wide association study identified substantial associations …